Citation Indices


Google Scholar (E and OE)

Web of Science



[CA = Corresponding Author][LA = Lead Author][BC = Book Chapter][R = Review/Editorial/Opinion] - E and OE .



258. M. Hassert, L.L. Pewe, R. He, M. Heidarian, P. Phruttiwanichakun, S. Van de Wall, M.R. Mix, A.K. Salem, V.P. Badovinac, and J.T. Harty. Regenerating murine memory CD8+ lung tissue resident memory T cells after targeted radiation exposure. Journal of Experimental Medicine. 2024.

257. A.K. Salem. Recent Advances in Drug Delivery. The AAPS Journal. 2024. [CA]

256. K. Atluri, J.A. Banas, J.L. Chakka, G. Avila-Ortiz S. Elangovan, A.K. Salem. Metronidazole loaded chitosan coatings as dental implants.  Emergent Materials. 2024. [CA]

255. D.S. Nakhla, A.I. Mekkawy, Y.W. Naguib, A.D. Silva, D. Gao, J.A. Kim, S.O. Alhaj-Suliman, T.M. Acri, S. Ernst, D.A. Stoltz, M.J. Welsh, A.K. Salem. Injectable long-acting ivacaftor-loaded poly (lactide-co-glycolide) microparticle formulations for the treatment of cystic fibrosis: in vitro characterization and in vivo pharmacokinetics in mice. International Journal of Pharmaceutics. 2024. [CA]

254. A. Hlas, V. Ganesh, J. Marks, R. He, A.K. Salem, J.A. Buckwalter, K.R. Duchman, K. Shin, J.A. Martin, D. Seol Buffering Mitigates Chondrocyte Oxidative Stress, Metabolic Dysfunction, and Death Induced by Normal Saline: Formulation of a Novel Arthroscopic Irrigant. International Journal of Molecular Sciences. 2024.



253. S. Areecheewakul, A. Adamcakova-Dodd, Z.R. Zacharias, X. Jing, D.K. Meyerholz, K.L. Legge, J.C.D. Houtman, P.T. O’Shaughnessy, P.S. Thorne, A.K. Salem. Immunomodulatory effects of sub-acute inhalation exposure to copper oxide nanoparticles in house dust mite-induced asthma. ACS Nano. 2023. [CA]

252. Y.W. Naguib, S.O. Alhaj-Suliman, E.I. Wafa, S. Saha, K. Ebeid, H.H.H. Mohammed, S.A. Abdel-Rahman, G.E.A. Abuo-Rahma, S.M. Geary, A.K. Salem. Ciprofloxacin derivative‐loaded nanoparticles synergize with paclitaxel against type II human endometrial cancer. Small. 2023. [CA]

251. S.O. Alhaj-Suliman, Y.W. Naguib, E.I. Wafa, S. Saha, K. Ebeid, X. Meng, H.H. Mohammed, G.A. Abuo-Rahma, S. Yang, A.K. Salem. A Ciprofloxacin Derivative with Four Mechanisms of Action Overcomes Paclitaxel Resistance in p53-Mutant and MDR1 Gene-Expressing Type II Human Endometrial Cancer. Biomaterials. 2023. [CA]

250. S. Tambunlertchai, S.M. Geary, Y.W. Naguib, A.K. Salem. Anti-melanoma effects of resiquimod (RSQ) in vitro and in combination with immune checkpoint blockade in vivo. The AAPS Journal. 2023. [CA]

249. A. McMillan, N. McMillan, N. Gupta, S. Kanotra, A.K. Salem. 3D Bioprinting in Otolaryngology: A Review. Advanced Healthcare Materials. 2023. [CA]

248. A. Ellis, S.M. Geary, A.K. Salem. Heterologous prime-boost vaccine using antigen-loaded microparticles and adenovirus (encoding antigen) enhances cellular immune responses and antitumor activity. International Journal of Pharmaceutics. 2023 [CA]

247. V. Ganesh, Y. Kancherla, C.M. Igram, A.J. Pugely, A.K. Salem, K. Shin, T. Lim, D. Seol. Pharmacotherapies to Prevent Epidural Fibrosis after Laminectomy: A Systematic Review of In Vitro and In Vivo Animal Models. Spine. 2023.

246. W.I. Malkawi, N.Z. Laird, P. Phruttiwanichakun, E. Mohamed, S. Elangovan, A.K. Salem. Application of lyophilized gene-delivery formulations to dental implant surfaces: non-cariogenic lyoprotectant preserves transfection activity of polyplexes long-term. Journal of Pharmaceutical Sciences. 2023. [CA]

245. S. Tambunlertchai, S.M. Geary, Y.W. Naguib, A.K. Salem. Investigating Silver Nanoparticles and Resiquimod as a Local Melanoma Treatment. European Journal of Pharmaceutics and Biopharmaceutics. 2023. [CA]

244. M.S. Petronek, N. Teferi, J.M. Caster, J.M. Stolwijk, A. Zaher, J.M. Buatti, D. Hasan, E. Wafa, A.K. Salem, E.G. Gillan, J.J. St – Aubin, G.R. Buettner, D.R. Spitz, V.A. Magnotta, B.G. Allen. Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate. Redox Biology. 2023.

243. A.K. Salem. Chlorine is a highly useful chemical that’s also extremely dangerous− here’s what to know about staying safe around it. The Conversation. 2023. [CA]

242. R.T. Mohie el-dien, B.K. Mahmoud, M.F. Abdelwahab, A.I.M. Khedr, M.S. Kamel, R.Yahia, N.M. Mohamed, A.E. Zawily, E.S. Kamel, A.K Salem, U.R. Abdelmohsen & M.A. Fouad. Paralemnalia thyrsoides-associated fungi: phylogenetic diversity, cytotoxic potential, metabolomic profiling and docking analysis. BMC Microbiology. 2023

241. A.H. Elmaidomy, A.E. Zawily, A.K. Salem, F.H. Altemani, N.A. Algehainy, A.H. Altemani, M.E. Rateb, U.R. Abdelmohsen, N.H. Shady. New Cytotoxic Dammarane Type Saponins from Ziziphus spina-christi. Scientific Reports. 2023 [CA]

240.    A.K. Salem. Pharmacokinetics, Modelling, Machine Learning, Analytical Assay Development, Dissolution, Antibodies and Drug Delivery. AAPS Newsmagazine. 2023.

239. W. Malkawi, A. Lutfi, M.K. Afghan, L.M. Shah, L. Costandy, A. Ramirez, T. George, F. Toor, A.K. Salem and P.M. Kasi. Circulating tumor cell enumeration, biomarker analyses, and kinetics in patients with colorectal cancer and other GI malignancies. Frontiers in Oncology. 2023.



238. R. Smith†, E.I. Wafa†, S.M. Geary†, K. Ebeid, S.O. Alhaj-Suliman, A.K. Salem. Cationic nanoparticles enhance T-cell tumor infiltration and antitumor immune response to a melanoma vaccine. Science Advances. 2022. [CA]

237. Z. Laird, P. Phruttiwanichakun, M. Zhu, J.A. Banas, S. Elangovan, A.K. Salem. CAGE ionic liquids inhibit both elastase activity and growth of oral bacteria.  Journal of Biomedical Materials Research: Part A. 2023. [CA]

236. D. Keefe; R. Smith; B. Gao, W.L. Malkawi, S.M. Geary; P.M. Kasi, S. Sharif; A.K. Salem; Fatima Toor. Colorectal Cancer Biosensor Using Vertically-Oriented Silicon Nanowires. IEEE Sensors. 2022. 

235. S.O. Alhaj-Suliman, E.I. Wafa, A.K. Salem. Engineering nanosystems for diagnostic and therapeutic applications in cancer. Advanced Drug Delivery Reviews. 2022. [CA]

234. J.B. Lesnak, D.S. Nakhla, A. Plumb, A. McMillan, S. Saha, N. Gupta, Y. Xu, P. Phruttiwanichakun, L. Rasmussen, D.K. Meyerholz, A.K. Salem, K.A. Sluka. Select Androgen Receptor Modulator Microparticle Formulation Reverses Muscle Hyperalgesia in Mouse Model of Widespread Muscle Pain. Pain. 2022. [CA]

233. M. M. Hasibuzzaman, R. He, I.N. Khan, R. Sabharwal, A.K. Salem, A.L. Simons. Characterization of CPH:SA microparticle-based delivery of interleukin-1 alpha for cancer immunotherapy. Bioengineering & Translational Medicine. 2022.

232. J. Quarterman, P. Phruttiwanichakun, D. Fredericks, A.K. Salem. Zoledronic Acid Implant Coating Results in Local Medullary Bone Growth. Molecular Pharmaceutics. 2022. [CA]

231. K.K. Moncal, M. Yeo, N.T. Celik, T. Acri, E.V. Rizk, H. Wee, G.S. Lewis, A.K. Salem and Ibrahim T. Ozbolat. Comparison of In-Situ versus Ex-Situ Delivery of Polyethylenimine-BMP-2 polyplexes for Rat Calvarial Defect Repair via Intraoperative Bioprinting. Biofabrication. 2022.

230. S. Areecheewakul, A. Adamcakova-Dodd, E. Haque, X. Jing, D.K. Meyerholz, P.T. O’Shaughnessy, P.S. Thorne, A.K. Salem. Time course of pulmonary inflammation and trace element biodistribution during and after sub-acute inhalation exposure to copper oxide nanoparticles in a murine model. Particle and Fibre Toxicology. 2022. [CA]

229. A. Scholp, J. Jensen, S. Chinnathambi, K. Atluri, A. Mendenhall, T. Fowler, A.K. Salem, J.A. Martin, E.A. Sander. Force-Bioreactor for Assessing Pharmacological Therapies for Mechanobiological Targets. Frontiers in Bioengineering and Biotechnology. 2022

228. K. Wiwatchaitawee*, K. Ebeid*, J.C. Quarterman, Y. Naguib, Y. Ali, C. Oliva, C. Griguer, A.K. Salem. Surface modification of nanoparticles enhances drug delivery to the brain and improves survival in a glioblastoma multiforme murine model. Bioconjugate Chemistry. 2022 [CA]

227. K.K. Moncal, R. Seda Tigli Aydın, K.P. Godzik, T.M. Acri, D.N. Heo, E. Rizk, H. Wee, G.S. Lewis, A.K. Salem, I.T. Ozbolat. Controlled Co-delivery of pPDGF-B and pBMP-2 from intraoperatively bioprinted bone constructs improves the repair of calvarial defects in rats. Biomaterials. 2022.

226. L. Liu, P.G. Kshirsagar, S.K. Gautam, M. Gulati, E.I. Wafa, J.C. Christiansen, B. White, S.K. Mallapragada, M.J. Wannemuehler, S. Kumar, J.C. Solheim, S.K. Batra, A.K. Salem*, B. Narasimhan*, M. Jain*. Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies. Theranostics. 2022. [CA]

225. Potential Role of Selenium in the Treatment of Cancer and Viral Infection. A.O. Rataan, S.M. Geary, Y.N. Zakharia, Y.M. Rustum*, A.K. Salem*. International Journal of Molecular Sciences. 2022. [CA]

224. J. Shin, Y. Xu, A.K. Salem. Gelation Properties and Drug Release Kinetics of a Thermoreversible Hydrogel as a Drug Carrier. Journal of Student Research. 2022. [CA]

223. MicroRNAs expression in clear cell renal cell carcinoma cell lines and tumor biopsies; potential therapeutic targets. S. Swearson, A.O. Rataan, S. Eliason, B.A. Amendt, Y. Zakharia, A.K. Salem, T.H. Ho, Y.M. Rustum. International Journal of Molecular Sciences. 2022.

222. B. Gao, A.A. Rojas Chavez, W.I. Malkawi, D. Keefe, R. Smith, H. Haim, A.K. Salem, F. Toor. Sensitive Detection of SARS-CoV-2 Spike Protein Using Vertically-Oriented Silicon Nanowire Array-Based Biosensor. Sensing and Bio-Sensing Research. 2022. 

221. S. Tambunlertchai, S.M. Geary, A.K. Salem. Topically Applied Resiquimod versus Imiquimod as a Potential Adjuvant in Melanoma Treatment. Pharmaceutics. 2022. [CA]

220. H.H.H. Mohammed, A.A. Abd El-Hafeez, K. Ebeid, A.I. Mekkawy, E.I. Wafa, A.K. Salem, A.M. Hayallah, P.Ghosh, G. El-Din A Abuo-Rahma,  S.H Abbas. New 1,2,3-Triazole Linked Ciprofloxacin-Chalcones induce DNA Damage by Inhibiting Human Topoisomerase I& II and Tubulin Polymerization. Journal of Enzyme Inhibition and Medicinal Chemistry.  2022. [CA]

219. A.K. Salem, J. Nguyen and K.M. Ainslie. The AAPS Journal Theme Issue: Rising Stars in Drug Delivery and Novel Carriers. The AAPS Journal. 2022. [CA]



218. M. Chandler, B. Johnson, E. Khisamutdinov, M.A. Dobrovolskaia, J. Sztuba-Solinska, A.K. Salem, K. Breyne, R. Chammas, N. Walter, L.M. Contreras, P. Guo, K.A. Afonin. The International Society of RNA Nanotechnology and Nanomedicine (ISRNN): The Present and the Future of the Burgeoning Field. ACS Nano. 2021

217. Z. Al-Qurayshi, E.I. Wafa, M.R. Meyer, S. Owen, A.K. Salem. Tissue Engineering the Pinna: Comparison and Characterization of Human Decellularized Auricular Biological Scaffold. ACS Applied Biomaterials. 2021 [CA]

216. J.C. Quarterman, Y.W. Naguib, J.L. Chakka, D. Seol, J.A. Martin, A.K. Salem. HPLC-UV Method Validation for Amobarbital and Pharmaceutical Stability Evaluation when Dispersed in a Hyaluronic Acid Hydrogel: A New Concept for Post-traumatic Osteoarthritis Prevention. Journal of Pharmaceutical Sciences. 2021. [CA]

215. K. Wiwatchaitawee*, A.I. Mekkawy*, J.C. Quarterman, Y.W. Naguib, K. Ebeid, S.M. Geary, A.K. Salem. The MEK 1/2 Inhibitor PD98059 Exhibits Synergistic Anti-endometrial Cancer Activity with Paclitaxel in vitro and Enhanced Tissue Distribution in vivo when Formulated into PAMAM-coated PLGA-PEG Nanoparticles. Drug Delivery and Translational Sciences. 2021. [CA]

214. A.I. Mekkawy, Y.W. Naguib, S.O. Alhaj-Suliman, E.I. Wafa, K. Ebeid, T. Acri, A.K. Salem. Paclitaxel anticancer activity is enhanced by the MEK 1/2 inhibitor PD98059 in vitro and by PD98059-loaded nanoparticles in BRAFV600E melanoma-bearing mice. International Journal of Pharmaceutics. 2021. [CA]

213. D. Seol, H.H. Choe, H. Zheng, M.J. Brouillette, D.C. Fredericks, E.B. Petersen, I. Song, L.R. Jaidev, A.K. Salem, J.A. Martin. Intra-Articular Adeno-Associated Virus-Mediated Proteoglycan 4 Gene Therapy for Preventing Post-Traumatic Osteoarthritis. Human Gene Therapy. 2021

212. Y.W. Naguib, S. Saha, J.M. Skeie, T. Acri, K. Ebeid, S. Abdel-rahman, S. Kesh, G.A. Schmidt, D.Y. Nishimura, J.A. Banas, M. Zhu, M.A. Greiner, A.K. Salem. Solubilized Ubiquinol for Preserving Corneal Function. Biomaterials. 2021 [CA]

211. N.Z. Laird, T.M. Acri, K. Tingle, A.K. Salem. Gene- and RNAi-Activated Scaffolds for Bone Tissue Engineering: Current Progress and Future Directions. Advanced Drug Delivery Reviews. 2021. [CA]

210. S. Sabree, A. Voigt, S. Blackwell, A. Vishwakarma, A.K. Salem, G.J. Weiner. Direct and Indirect Immune Effects of CMP-001, a Virus Like Particle Containing a TLR9 Agonist. Journal of Immunotherapy of Cancer. 2021

209. S.A. Abdel-Rahman, E.I. Wafa, K. Ebeid, S.M. Geary, Y.W. Naguib, A.K. El-Damasy, A.K. Salem. Thiophene derivative-loaded nanoparticles mediate anticancer activity through the inhibition of kinases and microtubule assembly. Advanced Therapeutics. 2021. [CA]

208. Z. Al-Qurayshi, E. Wafa, H. Hoffman, K. Chang, A.K. Salem. Tissue-engineering the Larynx: Effect of Decellularization on Human Laryngeal Framework and the Cricoarytenoid Joint. Journal of Biomedical Materials Research: Part B - Applied Biomaterials. 2021. [CA]

207. S.A. Sabree, C.D. Lemke-Miltner, S.E. Blackwell, C.Yin, A. Bossler, K. Ebeid, A.K. Salem, G.J. Weiner. Monocytes Exposed to Immune Complexes Reduce pDC Type 1 Interferon Response to Vidutolimod. Vaccines. 2021.

206. A.K. Salem and X. Lu. National Institute for Pharmaceutical Technology & Education (NIPTE) Research and Perspective: Advances in Nanotechnology-Based Drug Delivery. AAPS PharmSciTech. 2021 [CA]

205. M. M. Hasibuzzaman, K. Ross, A.K. Salem, B. Narasimhan, A.L. Simons. Evaluation of the In Vivo Antitumor Activity of Polyanhydride IL-1α Nanoparticles. Journal of Visualized Experiments. 2021.

204. A.S. Lu, M. Rouhimoghadam, C.K. Arnatt, E.J. Filardo, A.K. Salem. Proteolytic targeting chimeras with specificity for plasma membrane and intracellular estrogen receptors. Molecular Pharmaceutics. 2021. [CA]

203. J.L. Chakka, T. Acri, N.Z. Laird, L. Zhong, K. Shin, S. Elangovan, A.K. Salem. Polydopamine Functionalized Vascular Endothelial Growth Factor Gene Activated Three-Dimensional Printed Scaffolds for Bone Regeneration. RSC Advances. 2021. [CA]

202. D. Seol, M.C. Coleman, J.A. Martin, I. Song, J.L.R. Chakka, A.K. Salem, and T.H. Lim. Targeting Oxidative Stress with Amobarbital to Prevent Intervertebral Disc Degeneration. The Spine Journal. 2021.

201. A.S. Morris, B.E. Givens, A. Silva, A.K. Salem. Copper oxide nanoparticle diameter mediates serum-sensitive toxicity in Beas-2B cells. Advanced NanoBiomed Research. 2021. [CA]

200. S. Tambunlertchai, S.M. Geary, A.K. Salem. Skin penetration enhancement strategies used in the development of melanoma topical treatments. The AAPS Journal. 2021. [CA]

199. Y. Cheng, N.Borcherding, A. Ogunsakin, C.D. Lemke-Miltner, K.N. Gibson-Corley, A.Rajan, A.B. Choi, W. Wongpattaraworakul, C.H.F. Chan, A.K. Salem, G.J. Weiner & A.L. Simons. The anti-tumor effects of cetuximab in combination with VTX-2337 are T cell dependent. Scientific Reports. 2021. 

198. T.L. Terry, B.E. Givens, A. Adamcakova-Dodd, P.S. Thorne, V.G.J. Rodgers, A.K. Salem.Encapsulating polyethyleneimine-DNA nanoplexes into PEGylated biodegradable microspheres microparticles increases transgene expression in vitro and reduces inflammatory responses in vivo. AAPS PharmSciTech.  2021. [CA]

197. N.Z. Laird, T. Acri, J.L. Chakka, J. Quarterman, W.I. Malkawi, S. Elangovan, A.K. Salem. Applications of nanotechnology in 3D printed tissue engineering scaffolds. European Journal of Pharmaceutics and Biopharmaceutics. 2021. [CA]

196. K. Wiwatchaitawee, J.C. Quarterman, S.M. Geary, A.K. Salem. Enhancement of therapies for glioblastoma (GBM) using nanoparticle based delivery systems. AAPS PharmSciTech. 2021. [CA]

195. N. Bocherding, A. Vishwakarma, A.P. Voigt, A. Bellizzi, J. Kaplan, K. Nepple, A.K. Salem, R.W. Jenkins, Y. Zakharia, W. Zhang. Mapping the Immune Environment in Clear Cell Renal Carcinoma by Single-Cell Genomics. Communications Biology. 2021.

194. K. Ebeid, S.M. Geary, A.K. Salem. Preparation and Characterization of a Liver Targeted, Poly(amidoamine) Based, Gene Delivery System. Methods in Molecular Biology. (Springer Nature). 2021 [CA]



193. B. Khorsand, T. Acri, A. Do, J. Femino, E. Petersen, D.C. Fredericks, A.K. Salem. A multi-functional implant induces bone formation in a diabetic model. Advanced Healthcare Materials. 2020. [CA]

192. J. Quarterman, S.M. Geary, A.K. Salem. Evolution of Drug Eluting Biomedical Implants for Sustained Drug Delivery. European Journal of Pharmaceutics and Biopharmaceutics. 2020. [CA]

191. H.R. Shrader, A.M. Miller, A. Tomanek-Chalkley, A. McCarthy, K.L. Coleman, P. Hien Ear, A.K. Mangalam, A.K. Salem, C.H.F. Chan. Effect of bacterial contamination in bile on pancreatic cancer cell survival. Surgery. 2020.

190. S.K. Boi, R.M. Orlandella, J.T. Gibson, W.J. Turbitt, G. Wald, L. Thomas, C.B. Rosean, K.E. Norris, M. Bing, L. Bertrand, B.P. Gross, A. Makkouk, D. Starenki, K.I. Farag, R.E. Sorge, J.A. Brown, J. Gordetsky, H. Yasin, R. Garje, L. Nandagopal, G.J. Weiner, D.M. Lubaroff, R.C. Arend, P. Li, Y. Zakharia, E. Yang, A.K Salem, K. Nepple, T.T. Marquez-Lago, L.A. Norian. Obesity diminishes response to PD-1-based immunotherapies in renal cancer. Journal of Immunotherapy in Cancer. 2020

189. P. Tyagi, V. Agrahari, A.K. Salem. Nanotechnology for Cancer Vaccines: Translational Challenges, Opportunities and Future Prospects. AAPS Newsmagazine. 2020.

188. M. Rouhimoghadam, A.S. Lu, A.K. Salem, E.J. Filardo. Therapeutic perspectives on the modulation of G-protein coupled estrogen receptor, GPER, function. Frontiers in Endocrinology. 2020

187. T.M. Acri, N.Z. Laird, L.R.J. Chakka, D.K. Meyerholz, A.K. Salem*, K. Shin*. Non-viral gene delivery embedded in biomimetically mineralized matrices for bone tissue engineering. Tissue Engineering, Part A. 2020. [CA]

186. R. Smith, S.M. Geary, A.K. Salem. Implications of Current and Future Approaches to COVID-19 Testing. Future Virology. 2020. [CA]

185. K.J. Bell, T.I. Lansakara, R. Crawford, T. Blake Monroe, A. Tivanski, A.K. Salem, L. Stevens. Mechanical cues protect against ROS-mediated silica nanoparticle toxicity in SH-SY5Y neuroblastoma. Toxicology In Vitro. 2020

184. Y. Cheng, C.D. Lemke-Miltner, W. Wongpattaraworakul, Z. Wang, C.H. Chan, A.K. Salem, G.J. Weiner, A.L. Simons. In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy. Journal for ImmunoTherapy of Cancer. 2020

183. B.P. Gross, K. Chitphet, A. Wongrakpanich, E. Wafa, L.A. Norian, and A.K. Salem. Biotinylated streptavidin surface coating improves the efficacy of a PLGA microparticle-based cancer vaccine. Bioconjugate Chemistry. 2020. [CA]

182. Y.W. Naguib, Y. Yu, S. Wei, A. Morris, B.E. Givens, A.I. Mekkawy, R.M. Weiss, R.B. Felder, A.K. Salem. An injectable microparticle formulation provides long-term inhibition of hypothalamic ERK1/2 activity and sympathetic excitation in rats with heart failure. Molecular Pharmaceutics. 2020. [CA]

181. S.A. Abdelrahman, A. El-Damasy, G.S. Hassan, E.I. Wafa, S.M. Geary, A.R. Maarouf, A.K. Salem. Cyclohepta-b-thiophenes as potential antiproliferative agents: Design, synthesis, in vitro and in vivo anticancer evaluation. ACS Pharmacology & Translational Science. 2020. [CA]

180. R.D. Smith, S.M. Geary, A.K. Salem Silicon Nanowires for Cancer Detection and Monitoring. ACS Applied Nanomaterials. 2020. [CA][R]

179. S. Elangovan, P. Gajendrareddy, S. Ravindran, A.K. Salem. Emerging Local Delivery Strategies to Enhance Bone Regeneration. Biomedical Materials. 2020. [CA]

178. L.R.J. Chakka, N.Z. Laird, T. Acri, S. Elangovan, A.K. Salem. Polydopamine Functionalized 3D Printed Scaffolds for Bone Tissue Engineering. Transactions on Additive Manufacturing Meets Medicine (Trans. AMMM - ISSN: 2699-1977). 2020. [CA]

177. J.M. Skeie, B.T. Aldrich, D.Y. Nishimura, G.A. Schmidt, M.B. Zimmerman, J.J. Ling, Y.W. Naguib, A.K. Salem, M.A. Greiner. Ubiquinol supplementation of donor tissue enhances corneal endothelial cell mitochondrial respiration. Cornea. 2020.

176. S.O. Suliman, G. Milavetz, A.K. Salem. Model-based meta-analysis comparing efficacy-endpoint, time course, safety, and tolerability of opioids used in management of osteoarthritic pain. Current Drug Metabolism. 2020 [CA]

175. Application of gene-activating BMP-2/FGF-2 scaffolds for dental pulp capping. *J. Chakka, *J. Vislisel, C. de Mattos Pimenta Vidal, M. Tillmann Biz, D. Dawson, ^A.K. Salem, ^B. Neves Cavalcanti. Clinical Oral Investigations. 2020 [CA]

174. Y.W. Naguib, B.E. Givens, G. Ho, Y. Yu, S. Wei, R.M. Weiss, R.B. Felder, A.K. Salem.  An injectable microparticle formulation for the sustained release of the specific MEK inhibitor PD98059: in vitro evaluation and pharmacokinetics. Drug Delivery and Translational Research. 2020. [CA]

173. K. Atluri, S. Chinnathambi, A. Mendenhall, J.A. Martin, E.A. Sander, A.K. Salem. Targeting Cell Contractile Forces: A Novel Minimally Invasive Treatment Strategy for Fibrosis. Annals of Biomedical Engineering. 2020. [CA]

172. J.H. Wilson-Welder, P. Boggiatto, J.E. Nally, E.I. Wafa, D.P. Alt , R.L. Hornsby, A. Frank, D.E. Jones, S.C. Olsen, N.B. Bowden, A.K. Salem. Bovine immune response to leptospiral antigen in different novel adjuvants and vaccine delivery platforms. Vaccine. 2020.

171. S. Areecheewakul, A. Adamcakova-Dodd, B.E. Givens,  B.R. Steines, Y. Wang, D.K. Meyerholz, N.J. Parizek, R. Altmaier, P.T. O’Shaughnessy, A.K. Salem*. P.S. Thorne*. Toxicity assessment of metal oxide nanomaterials using in vitro screening and murine acute inhalation studies. Nanoimpact. 2020. [CA]

170. Y. Wang, A. Adamcakova-Dodd, B.R. Steines, X.Jing, A.K. Salem, P.S. Thorne. Comparison of in vitro toxicity of aerosolized engineered nanomaterials using air-liquid interface mono-culture and co-culture models. Nanoimpact. 2020.

169. N. Z. Laird, J.L. Chakka, T. Acri, S. Elangovan, A.K. Salem. A Proof of Concept Gene-Activated Titanium Surface for Oral Implantology Applications. Journal of Tissue Engineering and Regenerative Medicine. 2020. [CA]

168. T.M. Acri, N.Z. Laird, L. Hong, J. Chakka, K. Shin, S. Elangovan, A.K. Salem. Inhibition of BMP-9 Induced Bone Formation by Salicylic-acid Polymer Capping. MRS Advances. 2020. [CA]

167. E.I. Wafa, J.H. Wilson-Welder, R.L. Hornsby, J.E. Nally, S.M. Geary, N.B. Bowden, A.K. Salem. Poly(diaminosulfide) Microparticle-Based Vaccine for Delivery of Leptospiral Antigens. Biomacromolecules. 2020. [CA]

166. K. Chitphet, S.M. Geary, C.H.F. Chan, A.L. Simons, G.J. Weiner, A.K. Salem. Combining Doxorubicin-Loaded PEGylated Poly(Lactide-co-glycolide) Nanoparticles with Checkpoint Inhibition Safely Enhances Therapeutic Efficacy in a Melanoma Model. ACS Biomaterials Science & Engineering. 2020. [CA]

165. A. Wongrakpanich, J. Sukasiriworaphong, S.M. Geary, P. Sawangchan, J. Intra, U. Ruktanonchai, A.K. Salem. Mitochondria-targeting particles for biomedical applications. Book Chapter in the Book titled “Mitochondrial Protection for Health and Aging: Using Natural Compounds to Improve Mitochondrial Function through the Lifecycle” (Elsevier). [BC][CA]

164. N.Z. Laird, J.L. Chakka, T. Acri, J.Quarterman, W.I. Malkawi, S. Elangovan, A.K. Salem. 3D Printed Scaffolds for Tissue Engineering. Invited Book Chapter in “Handbook of Nanotechnology Applications.” Elsevier. 2020. [CA][BC]

163. J.C. Quarterman, B.E. Givens, S.M. Geary, A.K. Salem. Drug Eluting Degradable Coatings on Biomedical Implants. Book Chapter in “Emerging Technologies for Biofabrication and Biomanufacturing”. (2019) Edited by El Assal, Chen and Demirci [CA][BC]



162 .E.I. Wafa, S.M. Geary, K. Ross, B. Narasimhan, A.K. Salem. Pentaerythritol-based lipid A bolsters the antitumor efficacy of a polyanhydride particle-based cancer vaccine. Nanomedicine: Nanotechnology, Biology, and Medicine. 2019.  [CA]

161. T.M. Acri#, K. Shin#, D. Seol, N.Z. Laird, I. Song, S.M. Geary, J.L. Chakka, J. Martin, A.K. Salem. Tissue engineering for the temporomandibular joint. Advanced Healthcare Materials. 2019. [CA][LA]

160. A. Do, R. Smith, P. Tobias, D. Carlsen, E. Pham, N.B. Bowden and A.K. Salem. Sustained Release of Hydrogen Sulfide (H2S) from Poly(lactic acid) Functionalized 4-hydroxythiobenzamide Microparticles to Protect against Oxidative Damage. Annals of Biomedical Engineering. 2019.  [CA]

159. J. Bi, S. Areecheewakul, Y. Li, S. Yang, Y. Zhang, K. Ebeid, L. Li , K. Thiel, J. Zhang, A.K. Salem, K.K. Leslie,  X. Meng. MTDH increase cisplatin resistance in cancer by associating with mRNAs of FANCD2 and FANCI. Gynecologic Oncology. 2019

158. T.M. Acri, N.Z. Laird, S.M. Geary, J.Chakka, A.K. Salem, K. Shin. Effects of calcium concentration on non-viral gene delivery to bone marrow-derived stem cells. Journal of Tissue Engineering and Regenerative Medicine. 2019. [CA] 

157. K. Atluri, M.J. Brouillette, D. Seol, B. Khorsand, E. Sander, A.K. Salem, D. Fredericks, E. Petersen, S. Smith, T.P. Fowler, J.A. Martin. Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. Journal of Orthopedic Research. 2019. 

156. K.K. Ahmed, M.A. Tamer, M.M. Ghareeb, A.K. Salem.  Recent Advances in Polymeric Implants. AAPS PharmSciTech. 2019. 

155. L. Amaral-Machado, W. Oliveira, E. Alencar, A.K. Cruz, H.A. Rocha, K. Ebeid, A.K. Salem, E. S.Egito. Bullfrog oil (Rana catesbeiana Shaw) induces apoptosis, in A2058 human melanoma cells by mitochondrial dysfunction triggered by oxidative stress. Biomedicine & Pharmacotherapy. 2019.

154. L. Hong, A. Akkouch, M. Zhu, M.R. Bustillos, S. Eliason, F. Qian, A.K. Salem, B.A. Amendt. MicroRNA-200c Attenuates Periodontitis by Modulating Proinflammatory and Osteoclastogenic Mediators. Stem Cells and Development. 2019

153. J. L. Chakka, A.K. Salem. 3D Printing in Drug Delivery Systems. Journal of 3D Printing in Medicine. 2019. [CA][R]

152. S.O. Suliman, E.I. Wafa, S.M. Geary, A.K. Salem. Polymeric particles as cancer vaccine vectors. American Pharmaceutical Review. 2019 [CA][R]

151. T.L. Terry, B.E. Givens, V.G.J. Rodgers, A.K. Salem. Tunable properties of poly-DL-lactide-monomethoxypolyethylene glycol porous microparticles for sustained release of polyethylenimine-DNA polyplexes. AAPS PharmSciTech. 2019. [CA]

150. A.K. Salem. Higher Education Institutions as a Fertile Environment for Inter-Disciplinary Research that Can Solve Complex Biological Problems. As Far as the Eye Can See: The Promises and Perils of Research and Scholarship in the 21st Century. 2019. (Edited by D. Reed; University of Iowa Press) [BC][LA][CA]



149. K. Ebeid, X. Meng, K.W. Thiel, A. Do, S.M. Geary, A. S. Morris, E.L. Pham, A. Wongrakpanich, Y.S. Chhonker, D.J. Murry, K.K. Leslie, A.K. Salem. Synthetically Lethal Nanoparticles for Treatment of Endometrial Cancer. Nature Nanotechnology. 2018. [CA]

148. M.C. Coleman, J.E. Goetz, M.J. Brouillette, D. Seol, M.C. Willey, E.B. Petersen, B. Khorsand, A.S. Morris, A.K. Salem, D.C. Fredericks, T.O. McKinley, J.A. Martin. Mitochondrial Responses to Intraarticular Fracture are a Disease-Modifying Target for Posttraumatic Osteoarthritis Prevention. Science Translational Medicine. 2018. 

147. E.I. Wafa, S.M. Geary, K.A. Ross, J.T. Goodman, B. Narasimhan, A.K. Salem. A single shot of a polyanhydride particle-based vaccine generates potent antigen-specific anti-tumor immune responses in vivo. Journal of Pharmacology and Experimental Therapeutics. 2018. [CA]

146. J. Carter, E. Brown, J. Grace, A.K. Salem, E.E. Irish, N. Bowden Improved growth of pea, lettuce, and radish plants using the slow release of hydrogen sulfide from GYY-4137. PLoS One. 2018.

145. K.S. Worthington, A. Do, B.A. Tucker and A.K. Salem. Two-Photon Polymerization as a Tool for Studying 3D Printed Topography-Induced Stem Cell Fate. Macromolecular Biosciences. 2018. [CA]

144. T. Kruger, B.E. Givens, T. Lansakara, K. Bell, H. Mohapatra, A.K. Salem, A. Tivanski, L. Stevens. Mechanosensitive endocytosis of high-stiffness, sub-micron microgels in macrophage and hepatocarcinoma cell lines. ACS Applied Bio Materials. 2018.

143. B. Khorsand#, S. Elangovan#, L. Hong, M. Kormann, A.K. Salem. A Bioactive Collagen Membrane that Enhances Bone Regeneration. Journal of Biomedical Materials Research. 2018.

142. R. Smith, W. Duan, J. Quaterman, A. Morris, C. Collie, M. Black, F. Toor,  A.K. Salem. Surface Modifying Doped Silicon Nanowire based Solar Cells for Applications in Bio-sensing. Advanced Technological Materials. 2018. [CA]

141. A. Do, K.S. Worthington, B.A. Tucker and A.K. Salem. Controlled Drug Delivery from 3D Printed Two-Photon Polymerized Poly(Ethylene Glycol) Dimethacrylate Devices. International Journal of Pharmaceutics. 2018. [CA]

140. B.E. Givens, Y.W. Naguib, S.M. Geary, E.J. Devor, A.K. Salem. Nanoparticle-based delivery of CRISPR/Cas9 genome editing therapeutics. The AAPS Journal. 2018. [CA]

139. A. Do, S.M. Geary, D. Seol, P. Tobias, D. Carlsen, N. Leelakanok, J.A. Martin, A.K. Salem. Combining Ultrasound and Intratumoral Administration of Doxorubicin-loaded Microspheres to Enhance Tumor Cell Killing. International Journal of Pharmaceutics. 2018. [CA]

138. Nanoparticle-Based CpG-ODN Therapy for Treating Allergic Asthma. Brittany E. Givens, Sean M. Geary and Aliasger K. Salem. Immunotherapy. 2018. [CA]

137. N. Leelakanok, S.M. Geary, A.K. Salem. Fabrication and Use of PLGA-based Formulations Designed for Modified Release of 5-Fluorouracil. Journal of Pharmaceutical Sciences. 2018. [CA]

136. N. Leelakanok, S.M. Geary, A.K. Salem. Antitumor Efficacy and Toxicity of 5-FU-loaded PLGA Pellets. Journal of Pharmaceutical Sciences. 2018. [CA]

135. A. Do, R. Smith, T.M. Acri, S.M. Geary, A.K. Salem. 3D Printing Technologies for 3D Scaffold Engineering. Book Chapter in “Functional three-dimensional tissue engineering scaffolds: Technologies and applications”, Edited by Deng and Kuiper (Elsevier). [CA][BC]




134. B. Khorsand, N. Nicholson, A. Do, J.E. Femino, J.A. Martin, E. Petersen, B. Guetschow, D.C. Fredericks, A.K. Salem. Regeneration of bone using synergistic FGF2 and BMP2 gene delivery in a diaphyseal long bone radial defect diabetic rabbit model. Journal of Controlled Release. 2017. [CA]

133.  K.K. Ahmed, S.M. Geary, and A.K. Salem. Surface engineering tumor cells with adjuvant-loaded particles for use as cancer vaccines. Journal of Controlled Release. 2017. [CA]

132. A. Schumacher, C. Gilmer, K. Atluri, A. Jugessur, A.K. Salem, N. Bowden, M.L. Raghavan, D. Hasan. Development and Evaluation of a Nanometer-Scale Hemocompatible and Antithrombotic Coating Technology for Commercially Available Intracranial Stents and Flow Diverters. ACS Applied Nanomaterials. 2017.

131. K. Shin, T. Acri, S.M. Geary, A.K. Salem. Biomimetic Mineralization of Biomaterials Using Simulated Body Fluids (SBFs) for Bone Tissue Engineering and Regenerative Medicine. Tissue Engineering Part A. 2017. [CA]

130. A.S. Morris, S.C. Sebag, J.D. Paschke, A. Wongrakpanich, K. Ebeid, M.E. Anderson, I.M. Grumbach and A.K. Salem. Cationic CaMKII Inhibiting Nanoparticles Prevent Allergic Asthma. Molecular Pharmaceutics. 2017. [CA]

129. J. Srivastava, C.L Robertson, K. Ebeid, M. Dozmorov, D. Rajasekaran, R. Mendoza, A. Siddiq, M.A. Akiel, N. Jariwala, X. Shen, J.J. Windlw, M.A. Subler, N.D. Mukhopadhyay, S. Giashuddin, S. Ghosh, Z. Lai, Y. Chen, P.B. Fisher, A.K. Salem, A. Sanyal, D. Sarkar. A Novel Role of Astrocyte Elevated Gene-1 (AEG-1) in Regulating Non-alcoholic Steatohepatitis (NASH). Hepatology. 2017.  [CA]

128. A. Wongrakpanich, A.S. Morris, S.M. Geary, M.L. Joiner, A.K. Salem. Surface-modified particles loaded with CaMKII inhibitor protect cardiac cells against mitochondrial injury. International Journal of Pharmaceutics. 2017. [CA]

127. E.I. Wafa, S.M. Geary, J.T. Goodman, B. Narasimhan, A.K. Salem. The Effect of Polyanhydride Chemistry in Particle-based Cancer Vaccines on the Magnitude of the Antitumor Immune Response. Acta Biomaterialia. 2017. [CA]

126. A.S. Morris, A.K. Salem. Surface Engineered Nanoparticles: Considerations for Biomedical Applications. Advanced Engineering Materials. 2017. [R][CA]

125. A.K. Salem. Recent Advances in Musculoskeletal Tissue Regeneration. The AAPS Journal. 2017. [R][LA][CA]

124. S. D'Mello#, K. Atluri#, S.M Geary, L. Hong, S. Elangovan, A.K. Salem. Bone Regeneration using Gene-Activated Matrices. The AAPS Journal. 2016 #Joint First Authors [CA][R]

123. K. Ebeid, H. Giang, A.K. Salem. A HPLC-UV Method for Simultaneous Determination of MK-1775 and AZD-7762 in both Acetonitrile-Aqueous Solution and Mouse Plasma. Journal of Chromatography B. 2017. [CA]

122. B. Khorsand, S. Elangovan, L.Hong, A. Dewerth, M. Kormann, A.K. Salem. A comparative study of the bone regenerative effect of chemically modified RNA encoding BMP-2 or BMP-9. The AAPS Journal. 2017. [CA]




121.  A.B. Plonka, B. Khorsand, N. Yu, J.V. Sugai, A.K. Salem, W.V. Giannobile, S. Elangovan. Effect of Sustained PDGF Non-Viral Gene Delivery on Repair of Tooth-Supporting Bone Defects.  Gene Therapy. 2016

120. T. Sharp, B. Khorsand, C. Fischer, S. Eliason , A.K. Salem, K. Brogden, B. Amendt, L. Hong. MicroRNA-200c directly targets and represses IL-6, IL-8, and CCL-5 expression and enhances osteogenic differentiation. PLoS One. 2016.

119. K.S. Worthington, B.J. Green, M. Rethwisch, L.A. Wiley, B.A. Tucker, and C.A.Guymon and A.K. Salem. Neuronal Differentiation of Induced Pluripotent Stem Cells on Surfactant Templated Chitosan Hydrogels. Biomacromolecules. 2016. [CA]

118. A. Do, A. Akkouch, B. Green, S.M. Geary, I. Ozbolat, A.K. Salem. Controlled and Sequential Delivery of Fluorophores from 3D Printed Alginate-PLGA Tubes. Annals of Biomedical Engineering. 2016. [CA]

117. S.M. Geary, A.S. Morris and A.K. Salem. Assessing the Impact of Engineered Nanomaterials on the Environment and Human Health. Journal of Allergy and Clinical Immunology. 2016. [CA][R]

116. K. Atluri, J. Lee, D. Seabold, S. Elangovan, A.K. Salem. Gene Activated Titanium Surfaces Promote In Vitro Osteogenesis. The International Journal of Oral & Maxillofacial Implants. 2016. [CA]

115. A. Wongrakpanich, I.A. Mudunkotuwa, S.M. Geary, A.S. Morris, K.A. Mapuskar, D.R. Spitz, V.H. Grassian and A.K. Salem. Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells. Environmental Science: Nano. 2016. [CA]

114. K. Atluri, A. De Jesus, S. Chinnathambi, M. Brouillette, J. Martin, A.K. Salem*, E. Sander*. Blebbistatin-Loaded Poly(D,L lactide-co-glycolide) Particles for Treating Arthrofibrosis. ACS Biomaterials Science & Engineering. 2016. [CA]

113. S. Elangovan, M.S.D. Kormann, B. Khorsand, A.K. Salem.  The Oral and Craniofacial Relevance of Chemically Modified RNA Therapeutics. Discovery Medicine. 2016. [CA][R]

112. K.S. Worthington, L.A. Wiley, A. Guymon, A.K. Salem and B.A. Tucker. Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous PLGA Scaffolds.  Journal of Ocular Pharmacology and Therapeutics. 2016. [CA]

111. K. Ahmed, S.M. Geary, A.K. Salem. Development and Evaluation of Biodegradable Particles Co-loaded with Antigen and the Toll-like Receptor Agonist, Pentaerythritol Lipid A, as a Cancer Vaccine. Journal of Pharmaceutical Sciences. 2016. [CA]

110. Nanotoxicity. A.S. Morris, A.K. Salem. Nanomedicine for Inflammatory Diseases.  (CRS Press, Taylor and Francis; Ed: L. Milane, M. Amiji). 2016. [CA][BC]

109. Production of adjuvant-loaded biodegradable particles for use in cancer vaccines. C.M. de Barros, E.I. Wafa, K. Chitphet, K. Ahmed, S.M. Geary, A.K. Salem. Vaccine Adjuvants: Methods and Protocols (Springer; Ed: C.B. Fox). 2016. [CA][BC]




108. A.S. Morris, A. Adamcakova-Dodd, S.E. Lehman, A. Wongrakpanich, P.S. Thorne, S.C. Larsen, A.K. Salem. Amine Modification of Nonporous Silica Nanoparticles Reduces Inflammatory Response Following Intratracheal Instillation in Murine Lungs. Toxicology Letters. 2015. [CA]

107. S.E. Lehman, A.S. Morris, P.S. Mueller, A.K. Salem, V.H. Grassian, S.C. Larsen. Silica Nanoparticle-Generated ROS as a Predictor of Cellular Toxicity: Mechanistic Insights and Safety by Design. Environmental Science: Nano. 2015. 

106. S. Elangovan*, B. Khorsand*, A. Do, L. Hong, A. Dewerth, M. Kormann, R.D. Ross, D.R. Sumner, C. Allamargot, and A.K. Salem. Chemically modified RNA activated matrix induced bone regeneration. Journal of Controlled Release. 2015. [CA]

105. N. Leelakanok, C.L Fischer, A.M. Bates, J.M. Guthmiller, G.K. Johnson, A.K. Salem, K.A. Brogden, N. Brogden Cytotoxicity of HBD3 for dendritic cells, normal human epidermal keratinocytes, hTERT keratinocytes, and primary oral gingival epithelial keratinocytes in cell culture conditions. Toxicology Letters. 2015. [CA]

104. S.R. D’Mello, S. Elangovan, A.K. Salem. FGF2 Gene Activated Matrices Promote Proliferation of Bone Marrow Stromal Cells. Archives of Oral Biology. 2015. [CA]

103. S.M. Geary, Q. Hu, V.B. Joshi, N.B. Bowden, A.K. Salem. Diaminosulfide based polymer microparticles as cancer vaccine delivery systems.  Journal of Controlled Release. 2015. [CA]

102. T.S. Long, A. Wongrakpanich, A. Do, A.K. Salem, N.B. Bowden. Long-term release of a thiobenzamide from a backbone functionalized poly(lactic acid). Polymer Chemistry. 2015. 

101. K.A. Ross, T.M. Brenza, A. Binnebose, Y. Phanse, A. Kanthasamy, H.Gendelman, A.K. Salem, L. Bartholomay, B. Bellaire, B. Narasimhan. Nano-enabled Delivery of Diverse Payloads across Complex Biological Barriers. Journal of Controlled Release. 2015. [R]

100. A. Wongrakpanich, M. Wu and A.K. Salem. Correlating Intracellular Non-viral Polyplex Localization with Transfection Efficiency using High-Content Screening. Biotechnology Progress. 2015. [CA] 

99. K. Atluri, D. Seabold, L. Hong, S. Elangovan, A.K. Salem. Nanoplex-Mediated Co-delivery of Fibroblast Growth Factor and Bone Morphogenetic Protein Genes Promotes Osteogenesis in Human Adipocyte-Derived Mesenchymal Stem Cells. Molecular Pharmaceutics. 2015. [CA]

98. D. Rajasekaran#, J. Srivastava#, K. Ebeid#, R. Gredler, M. Akiel, N. Jariwala, C. L. Robertson, X. Shen, A. Siddiq, P.B. Fisher, A.K. Salem*, D. Sarkar*. Combination of nanoparticle-delivered siRNA for Astrocyte elevated gene-1 (AEG-1) and all-trans retinoic acid (ATRA): an effective therapeutic strategy for hepatocellular carcinoma (HCC). Bioconjugate Chemistry. 2015 #Joint First Authors *Corresponding Authors. [CA]

97. A. Do, B. Khorsand, S.M. Geary, A.K. Salem. 3D Printing of Scaffolds for Tissue Regeneration Applications. Advanced Healthcare Materials. 2015. [CA][R]

96. M. Flores, C. Chew, K. Tyan, W.Q. Huang, A.K. Salem and R. Clynes. FcγRIIB Prevents Inflammatory Type I IFN Production from Plasmacytoid Dendritic Cells during a Viral Memory Response. Journal of Immunology. 2015. 

95. A. Makkouk, V.B Joshi, C.D. Lemke, A. Wongrakpanich, A.K Olivier, S.E. Blackwell, A.K. Salem, G.J. Weiner. Three Steps to Breaking Tolerance to Lymphoma: A Microparticle Approach. Cancer Immunology Research. 2015. 

94. A. Makkouk, V.B. Joshi, A. Wongrakpanich, C.D. Lemke, B.P. Gross, A.K. Salem, G.J. Weiner. Biodegradable Microparticles Loaded with Doxorubicin and CpG for In Situ Immunization Against Tumors. The AAPS Journal. 2015. 

93. A.K. Salem. Nanoparticles in Vaccine Delivery. The AAPS Journal. 2015. [CA][R]

92. S.R. D’Mello, S. Elangovan, L. Hong, R.D. Ross, D.R. Sumner, and A.K. Salem. A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects. Current Pharmaceutical Biotechnology. 2015. [CA]

91. V.B. Joshi, A.A. Dodd, X. Jing, A. Wongrakpanich, K. Gibson-Corley, P.S. Thorne and A.K. Salem. Development of a poly (lactic-co-glycolic acid) particle vaccine to protect against house dust mite induced allergy. The AAPS Journal. 2014. [CA]

90. S.R. D’Mello, S. Elangovan, L. Hong, R.D. Ross, D.R. Sumner, and A.K. Salem. Incorporation of copper into chitosan scaffolds promotes bone regeneration in rat calvarial defects. Journal of Biomedical Materials Research: Part B - Applied Biomaterials. 2015. [CA]

89. A.S. Morris, A. Wongrakpanich, S.M. Geary, A.K. Salem. Microparticles and Nanoparticles for Cancer Targeting Vaccines. Book Chapter in “Micro and Nanotechnology in Vaccine Development, 1st edition by Skwarczynski & Toth (Elsevier). [CA][BC]




88. S.M. Geary and A.K. Salem. Exploiting the tumor phenotype using biodegradable submicron carriers of chemotherapeutic drugs. Critical Reviews in Oncogenesis. 2014. [CA][R]

87. K.K. Ahmed, S.M. Geary and A.K. Salem. Applying biodegradable particles to enhance cancer vaccine efficacy. Immunologic Research. 2014. [CA][R]

86. A. Wongrakpanich, A.A. Dodd, W. Xie, V.B. Joshi,  K.A. Mapuskar, D.R. Spitz, P.S. Thorne and A.K. Salem. The Absence of CpG in Plasmid DNA-Chitosan Polyplexes Enhances Transfection Efficiencies and Reduces Inflammatory Responses in Murine Lungs. Molecular Pharmaceutics. 2014. [CA]

85. B.P. Gross, A. Wongrakpanich, M.B. Francis, A.K. Salem, and L.A. Norian. Therapeutic microparticle-based tumor lysate vaccine reduces spontaneous metastasis in murine breast cancer. The AAPS Journal. 2014. 

84. A.K. Salem. A promising CpG adjuvant loaded nanoparticle based vaccine for treatment of dust mite allergies. Immunotherapy. 2014. [CA][R]

83. K.S. Worthington, L.A. Wiley, A.M. Bartlett; E.M. Stone, R.F. Mullins, A.K. Salem, A. Guymon, B.A Tucker.  Mechanical Properties of Murine and Porcine Ocular Tissues in Compression. Experimental Eye Research. 2014. 

82. A. Wongrakpanich, S.M. Geary, M.A. Joiner, M.E. Anderson, A.K. Salem. Mitochondria-targeting particles. Nanomedicine. 2014. [CA][R]

81. S. Elangovan, S.R. D’Mello, L. Hong, R.D. Ross, C. Allamargot, D.V. Dawson, C.M. Stanford, G.K. Johnson, D.R. Sumner, and A.K. Salem. The Enhancement of Bone Regeneration by Gene Activated Matrix Encoding for Platelet Derived Growth Factor. Biomaterials. 2014. [CA]

80. S. D’Mello, A.K. Salem, L. Hong, and S. Elangovan. Characterization and Evaluation of the Efficacy of Cationic Complex Mediated Plasmid DNA Delivery in Human Embryonic Palatal Mesenchyme Cells. Journal of Tissue Engineering and Regenerative Medicine. 2014. [CA]

79. A.K. Salem. Recent progress on the development of gene activated scaffolds encoding platelet derived growth factor for enhanced bone regeneration. Regenerative Medicine. 2014. [CA][R]

78. S.M. Geary, A.K. Salem. Vaccines. Encyclopedia of Cancer and Society, Second Edition. Edited by Graham A. Colditz and J. Geoffrey Golson. 2014. [CA][BC]

77. A. Do, B. Khorsand, S.M. Geary, A.K. Salem. Melanoma. Encyclopedia of Cancer and Society, Second Edition. Edited by Graham A. Colditz and J. Geoffrey Golson. 2014. [CA][BC]

76. K. Ahmed, A. Al-Jumaili, S.M. Geary, A.K. Salem. Cancer in Iraq. Encyclopedia of Cancer and Society, Second Edition. Edited by Graham A. Colditz and J. Geoffrey Golson. 2014. [CA][BC]

75. A.K. Salem. Holden Comprehensive Cancer Center at The University of Iowa. Encyclopedia of Cancer and Society, Second Edition. Edited by Graham A. Colditz and J. Geoffrey Golson. 2014. [LA CA][BC]




74. S.M. Geary, C.D. Lemke, D.M. Lubaroff, A.K. Salem. Proposed mechanisms of action for prostate cancer vaccines. Nature Reviews Urology. 2013. [CA][R]

73. C.D. Lemke, S.M. Geary, V.B. Joshi, A.K. Salem. Antigen coated poly α-hydroxy acid based microparticles for heterologous prime-boost adenovirus based vaccinations. Biomaterials. 2013. [CA]

72. S.M. Geary, C.D. Lemke, D.M. Lubaroff and A.K. Salem. The combination of a low-dose chemotherapeutic agent, 5-fluorouracil, and an adenoviral tumor vaccine has a synergistic benefit on survival in a model tumor system. PLoS ONE. 2013. [CA]

71. K.L.S. Worthington, A.A. Dodd, A.Wongrakpanich, I.A. Mudunkotuwa, K.A. Mapuskar, V.B. Joshi,  C. A.Guymon, D.R. Spitz, V.H. Grassian, P.S. Thorne and A.K. Salem. Chitosan coating of copper nanoparticles reduces in vitro toxicity and increases inflammation in the lung. Nanotechnology. 2013. [CA]

70. V.B. Joshi, S.M. Geary, B.R. Carrillo-Conde, B. Narasimhan, A.K. Salem. Characterizing the anti-tumor response in mice treated with antigen-loaded polyanhydride microparticles. Acta Biomaterialia. 2013. [CA]

69. V.B. Joshi, S.M. Geary, A.K. Salem. Biodegradable particles as vaccine delivery systems: Size matters. The AAPS Journal. 2013. [CA]

68. S. D'Mello, J. Yoo, N.B. Bowden, and A.K.  Salem. Microparticles prepared from sulfenamide-based polymers. Journal of Microencapsulation. 2013. [CA]

67. V.B. Joshi, S.M. Geary, B.P. Gross, A. Wongrakpanich, L.A. Norian, A.K. Salem. Tumor lysate-loaded biodegradable microparticles as cancer vaccines. Expert Review of Vaccines. 2013. [CA][R]

66. S.M. Geary, A.K. Salem. Human prostate cancer vaccines - clinical trials update. OncoImmunology. 2013. [CA][R]

65. V.B Joshi, S.M. Geary, A.K. Salem. Biodegradable particles as vaccine antigen delivery systems for stimulating cellular immune responses. Human Vaccines & Immunotherapeutics. 2013. [CA][R]

64. N. Wei, Y. Yu, V. Joshi, T. Schmidt, F. Qi-an, A.K. Salem, C. Stanford, L. Hong. Glucocorticoid receptor Antagonist and siRNA Prevent Senescence of Human Bone Marrow Mesenchymal Stromal Cells in vitro. Cell and Tissue Research. 2013. 

63. K. K. Ahmed, S.M. Geary and A.K. Salem. Invited Book chapter entitled “Engineering the surface of cells using the biotin-avidin interaction” in the Book “Micro- and Nanoengineering of the Cell Surface” (Elsevier). Edited by Weian Zhao (UCI) and Jeffrey Karp (Harvard). [CA][BC]




62. S. Krishnamurthy, M.A. Behlke, S. Ramchandran, A.K. Salem, P.B. McCray Jr, B.L. Davidson. Manipulation of Cell Physiology Enables Gene Silencing in Well-Differentiated Airway Epithelia. Molecular Therapy - Nucleic Acids. 2012. 

61. R.M. Walk, S.T. Elliot, F.C. Blanco, J.A. Snyder, A. Jacobi, S. Rose, M. Behlke, A.K. Salem, S. Vukmanovic, A.D. Sandler. T-cell activation is enhanced by targeting IL-10 cytokine production in toll-like receptor-stimulated macrophages. ImmunoTargets and Therapy. 2012. 

60. H.M. Rosevear, Y. Krishnamachari, C.A. Ariza, S.K. Mallapragada, A.K. Salem, T.S. Griffith,  B.R. De Young, M. Wald. Effect of combined locally delivered growth factors and systemic sildenafil citrate on the number of micro-recanals in a biodegradable conduit for reconstruction of the vas deferens. Urology. 2012. 

59. J. Yoo, D. Kuruvilla, S.R. D’Mello, A.K. Salem, and N.B. Bowden. New class of biodegradable polymers formed from reactions of an inorganic functional group. Macromolecules. 2012. 

58. J. Yoo, S.R. D’Mello, T. Graf, A.K. Salem, and N.B. Bowden. Synthesis of the first poly(diaminosulfide)s and an investigation of their applications as drug delivery vehicles. Macromolecules. 2012. 

57. A.K. Salem, S. Patil, D.J. Burgess. Recent progress in non-viral nucleic acids delivery. International Journal of Pharmaceutics. 2012. [CA LA][R]

56. L. Hong, N. Wei, V. Joshi, Y. Yu, N. Kim, Y. Krishnamachari, Q. Zhang, A.K. Salem. Effects of glucocorticoid receptor siRNA delivered by poly lactic-co-glycolic acid microparticles on proliferation and differentiation capabilities of human mesenchymal stromal cells. Tissue Engineering, Part A. 2012. [CA]

55. A. Wongrakpanich, V.B. Joshi, A.K. Salem. Poly(galactaramidoamine) is an efficient cationic polymeric non-viral vector with low cytotoxicity for transfecting human embryonic kidney (HEK293) and murine macrophage (RAW264.7) cells. Pharmaceutical Development and Technology.  2012. [CA]

54. N. Kim, D. Jiang, A. Jacobi, K.A. Lennox, S. Rose, M.A. Behlke, A.K. Salem. Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA. International Journal of Pharmaceutics. 2012. [CA]

53. D. Jiang, A.K. Salem. Optimized dextran-polyethylenimine conjugates are efficient non-viral vectors with reduced cytotoxicity when used in serum containing environments. International Journal of Pharmaceutics. 2012. [CA]

52. V.B. Joshi, S.M. Geary, A.K. Salem. Production of antigen-loaded nanoparticles and uptake by antigen-presenting cells.  Invited Chapter in the Book entitled ‘Cancer Vaccines Methods and Protocols. Methods in Molecular Biology.  Springer verlag Humana press.  Edited by Michael Lawman. 2012. [CA][BC]




51. C.D Lemke, J.B. Graham, S.M. Geary, G. Zamba, D.M. Lubaroff, A.K. Salem. Chitosan is a surprising negative modulator of cytotoxic CD8+ T cell responses elicited by adenovirus cancer vaccines. Molecular Pharmaceutics. 2011. [CA]

50. S.M. Geary, C.D. Lemke, D.M. Lubaroff, A.K. Salem. Tumor immunotherapy using adenovirus vaccines in combination with intratumoral doses of CpG ODN. Cancer Immunology, Immunotherapy. 2011. [CA]

49. D.A. Santillan, K.K. Rai, M.K. Santillan, Y. Krishnamachari, A.K. Salem and S. Hunter. Efficacy of Polymeric Encapsulated C5a peptidase-based Group B Streptococci Vaccines in a Murine Model. American Journal of Obstetrics & Gynecology. 2011. 

48. C.D. Lemke, J.B. Graham, D.M. Lubaroff, A.K. Salem. Development of an MHC class I Ld-restricted PSA peptide-loaded tetramer for detection of PSA-specific CD8+ T cells in the mouse. Prostate Cancer and Prostatic Diseases. 2011. [CA]

47. J. Intra, X.Q. Zhang, R.L. Williams, X. Zhu, A.D. Sandler, A.K. Salem. Immunostimulatory sutures that treat local disease recurrence following primary tumor resection. Biomedical Materials 2011. [CA]

46. L. Hong, Y. Krishnamachari, D. Seabold, V. Joshi, G. Schneider, A.K. Salem. Intracelluar release of 17-β estradiol from cationic polyamidoamine dendrimer surface modified poly lactic-co-glycolic acid microparticles improves osteogenic differentiation of human mesenchymal stromal cells. Tissue Engineering Part C: Methods  Vol 17, Iss 3, 319-325, 2011.  [CA]

45. Y. Krishnamachari, S.M. Geary, C.D. Lemke, A.K. Salem. Nanoparticle delivery systems in cancer vaccines. Pharmaceutical Research. Vol 28, Iss 2, 215-236, 2011. [CA][R]

44. J. Intra, A.K. Salem. Rational design, fabrication, characterization and in vitro testing of biodegradable microparticles that generate targeted and sustained transgene expression in HepG2 liver cells. Journal of Drug Targeting. 2011. [CA]

43. A.K. Salem, M. Behlke. siRNA Delivery Vehicles. Pharmaceutical Formulations and Quality. 2011. [CA LA][BC]

42. S.M. Geary, C.D. Lemke, Y. Krishnamachari, A.K. Salem. New nanobiotechnological strategies for the development of vectors for cancer vaccines.  Invited Chapter in the Book entitled ‘Pharmaceutical Biotechnology 2nd Edition‘. Wiley-Blackwell.  Edited by Oliver Kayser and Herbert Warzecha. 2011. [CA][BC]

41. D.J. Kuruvilla and A.K. Salem.  Nanotechnology and nanomedicine in diabetes: an overview. Invited Chapter in the Book entitled ‘Nanotechnology and nanomedicine in diabetes‘. Science Publishers.  Edited by Victor R. Preedy. 2011. [CA][BC]




40. J. Intra, A.K. Salem. Fabrication, characterization and in vitro evaluation of poly lactic-co-glycolic acid microparticles loaded with polyamidoamine-plasmid DNA dendriplexes for applications in non-viral gene delivery. Journal of Pharmaceutical Sciences Volume: 99   Issue: 1   Pages: 368-384. 2010. [CA]

39. A.K. Salem, M. Behlke. siRNA Delivery Vehicles. Invited Chapter in the Book entitled "RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development". John Wiley & Sons Inc. Edited by Paul H. Johnson. 2010. [LA CA][BC]

38. A. Petushkov, N. Ndiege, A.K. Salem, S.C. Larsen. Toxicity of Silica Nanomaterials: Zeolites, Mesoporous Silica, and Amorphous Silica Nanoparticles. Advances in Molecular Toxicology V4. 2010. [CA][BC]




37. A. Petushkov, J. Intra, J.B. Graham, S.C. Larsen, A.K.Salem. Effect of Crystal Size and Surface Functionalization on the Cytotoxicity of Silicalite-1 Nanoparticles. Chemical Research in Toxicology. Volume: 22   Issue: 7   Pages: 1359-1368. 2009. [CA]

36. R. Goforth, A.K. Salem, X. Zhu, S. Miles, X.Q. Zhang, J. Lee, A.D. Sandler. Immune Stimulatory Antigen Loaded Particles Combined with Depletion of Regulatory T-cells Induce Potent Tumor Specific Immunity in a Mouse Model of Melanoma. Cancer Immunology, Immunotherapy 58 (4) 517-30 Apr 2009. 

35. A.K. Salem and G.J. Weiner. CpG Oligonucleotides as Immunotherapeutic Adjuvants: Innovative Applications and Delivery Strategies. Advanced Drug Delivery Reviews. 61 (2009) 193-194. [CA LA][R]

34. Y. Krishnamachari and A.K. Salem. Innovative Strategies for Co-delivering Antigens and CpG Oligonucleotides. Advanced Drug Delivery Reviews. 61 (2009) 205-217. [CA][R]




33. J. Intra, A.K. Salem. Characterization of the Transgene Expression Generated by Branched and Linear Polyethylenimine (PEI)-Plasmid DNA Nanoparticles In Vitro and After Intraperitoneal Injection In Vivo. Journal of Controlled Release. (130) 129-138 2008. [CA]

32. M. Pearce, B. Mai, N. Lee. S.C. Larsen, A.K. Salem. Silicalite Nanoparticles that Promote Transgene Expression. Nanotechnology (19) 17 Article Number: 175103 2008. [CA]

31. J. Intra, J.M Glasgow, H. Q. Mai, A.K. Salem. Pulsatile Release of Biomolecules from Polydimethylsiloxane (PDMS) Chips with Hydrolytically Degradable Seals. Journal of Controlled Release (127) 280-287. 2008. [CA]

30. J.D. Clapper, M.E. Pearce, C.A. Guymon, A.K. Salem. Biotinylated Biodegradable Nanotemplated Hydrogel Networks for Cell Interactive Applications. Biomacromolecules  (9) 1188-1194. 2008. [CA]

29. Y. Krishnamachari, M.E. Pearce, A.K. Salem. Self-assembly of Cell-Microparticle Hybrids. Advanced Materials. (20) 5 989-993. 2008. [CA]

28. A. O. Abbas, M.D. Donovan, A.K. Salem. Formulating PLGA Particles for Plasmid DNA Delivery. Journal of Pharmaceutical Sciences. 97(7): 2448-61.July. 2008.  [CA][R]

27. X.Q. Zhang, J. Intra, A.K. Salem. Comparative Study of Poly (lactic-co-glycolic acid)-Poly Ethyleneimine-Plasmid DNA Microparticles Prepared Using Double Emulsion Methods. Journal of Microencapsulation. (25) 1-13. 2008. [CA]

26. J.B. Graham, M.E. Pearce, A.K. Salem. Multifunctional, Spherical & Anisotropic Metal and Metal Oxide Nanomaterials in Medical Diagnosis and Therapy. Invited Chapter in "Nanomaterials for the Life Sciences – Volume 3". Wiley-VCH. Edited by Challa Kumar. 2008. [CA][BC]

25. Y. Krishnamachari, A.K. Salem. Nano-Bio Polymers and Composites. Invited chapter in "Nano-and Biocomposites". Taylor & Francis/CRC Press 2008. Edited by Lau and Hussain. [CA][BC]

24. J. Glasgow, A.K. Salem. Stem Cells and Cancer. Invited review for Encyclopedia of Stem Cell Research. Sage Publications. Edited by Clive Niels Svendsen, Ph.D., Allison D. Ebert, Ph.D. and Geoffrey J. Golson, Ph.D.  2008. [CA][BC]

23. M.E. Pearce, A.K. Salem. Stem Cells and Iowa. Invited review for Encyclopedia of Stem Cell Research. Sage Publications. Edited by Clive Niels Svendsen, Ph.D., Allison D. Ebert, Ph.D. and Geoffrey J. Golson, Ph.D.  2008. [CA][BC]

22. A.K. Salem. Biopharmaceutical Drug Design and Development 2nd Ed. Journal of Medicinal Chemistry. 2008. [CA][R]

21. A.K. Salem. Frontiers in Drug Design and Discovery. Vol. 3 Journal of Medicinal Chemistry. 51(4):1073. 2008.  [CA][R]




20. X.Q. Zhang, J. Intra, A.K. Salem. Conjugation of Polyamidoamine Dendrimers on Biodegradable Microparticles for Non-Viral Gene Delivery. Bioconjugate Chemistry. 2007 Nov-Dec;18(6):2068-76.  [CA]

19. M.E. Pearce, J.B. Melanko, A.K. Salem. Biomedical Applications of Multifunctional Nanorods. Pharmaceutical Research. 2007. Dec; 24(12):2335-52. [CA][R]

18. X.Q Zhang, C.E. Dahle, G.J. Weiner, A.K. Salem. A Comparative Study on the Immune Response Stimulated from Co-delivery of CpG ODN and Antigens using Fusion Molecules or Biodegradable Microparticles. Journal of Pharmaceutical Sciences. 2007 Dec;96(12):3283-92. [CA]

17. X.Q. Zhang, C.E. Dahle, N.K. Baman, N. Rich, G.J. Weiner, A.K. Salem. Potent Antigen-Specific Immune Responses Stimulated by Co-delivery of CpG ODN and Antigens in Degradable Microparticles.  Journal of Immunotherapy. 30 (5): 469-478 July/August 2007. [CA]

16. J.B. Melanko, M.E. Pearce, A.K. Salem. Nanotubes/Nanorods/Nanofibers/Fullerenes for Nanoscale Drug Delivery. Invited Chapter in the Book entitled "Nanotechnology in Drug Delivery". Springer Science/AAPS. Edited by Melgardt M. de Villiers, and Glen S. Kwon. 2007.  [CA][BC]

15. M. Popescu, A.K. Salem. Nanostructure Enabled Vaccines. Invited Chapter in the "Exploring Nano-Biotechnology Multimedia Encyclopedia. iMediasoft. 2007. [CA][BC]

14. A.K. Salem, M.K. Salem, H.K. Salem, S. Tapya. New Technologies and Therapies for Cancer. Invited review for Encyclopedia of Cancer and Society. Sage Publications. Edited by J. Geoffrey Golson and Graham A. Colditz. 2007. [CA LA][BC]




13. N.K. Baman, G.B. Schneider, T.L. Terry, R. Zaharias, A.K. Salem. Spatial Control over Cell Attachment by Partial Solvent Entrapment of Poly Lysine in Microfluidic Channels. International Journal of Nanomedicine. 1 (2) APR 2006. [CA]

12. J. Sinclair, A.K. Salem. Rapid Localized Cell Trapping on Biodegradable Polymers Using Cell Surface Derivatization and Microfluidic Networking. Biomaterials 27 2090-2094 MAR 2006. [CA]

11. A.K. Salem, K.W. Leong. Polymer Scaffolds for Tissue Engineering and Gene Delivery. Invited Chapter in the Book entitled "Scaffolding in Tissue Engineering". Marcel Dekker. Edited by Jennifer Elisseeff and Peter X. Ma. 2006. [CA][BC]

10. A.K. Salem. Frontiers in Drug Design and Discovery. Vol. 2 Journal of Medicinal Chemistry. 2006. [CA][R]



9. A.K. Salem, C.F. Hung, T.W. Kim, T.C. Wu, P.C. Searson, K.W. Leong. Multi-Component Nanorods for Vaccination Applications. Nanotechnology. 4 (16): 484-487 APR 2005. [LA CA]

8. A. Hultgren, M. Tanase, E.J. Felton, K. Bhadriraju, A.K. Salem, C.S. Chen, D.H. Reich. Optimization of Yield in Magnetic Cell Separations using Nickel Nanowires of Different Lengths. Biotechnology Progress. 21 (2): 509-515. MAR-APR 2005.  




7. A.K. Salem, M. Chen, J. Hayden, K.W. Leong, and P.C. Searson. Directed Assembly of Multi-Segment Au/Pt/Au Nanowires. Nanoletters. 4 (6): 1163-1165 JUN 2004. [LA]

6. A.K. Salem, J. Chao, K.W. Leong, and P.C. Searson. Receptor Mediated Self-Assembly of Multi-Component Magnetic Nanowires. Advanced Materials.  FEB 2004, 16, 3. [LA]




5. A.K. Salem, P.C. Searson and K.W. Leong. Multifunctional Nanorods for Gene Delivery. Nature Materials.  OCT 2003, 2, 668-671. [LA]

4. H.S. Sakhalkar, M.K. Dalal, A.K. Salem, R. Ansari, J. Fu, M.F. Kiani, J. Hanes, K.M. Shakesheff and D.J. Goetz. Leukocyte Inspired Therapeutic Particles that Selectively and Avidly Adhere to Inflamed Endothelium in Vitro and in Vivo.  Proceedings of the National Academy of Sciences. DEC 2003, 100, 26:15895-15900 

3. A.K. Salem, F.R.A.J. Rose, R. Oreffo, X. Yang, M.C. Davies, J.R. Mitchell, C.J. Roberts, S. Stolnik, S.J.B. Tendler, P.M. Williams and K.M. Shakesheff. Porous Polymer and Cell Composites that Self assemble In Situ. Advanced Materials. FEB 2003, 15, 3. [LA]




2. A.K. Salem, R. Stevens, R.G. Pearson, M.C. Davies, S.J.B. Tendler and K.M. Shakesheff. Interactions of 3T3 Fibroblasts and Endothelial with Defined Pore Features.  Journal of Biomedical Materials Research. 61 (2) 212-217 AUG 2002. [LA]




1. A.K. Salem, S.M. Cannizzaro, M.C. Davies, S.J.B. Tendler, C.J. Roberts, P.M. Williams and K.M. Shakesheff. Synthesis and Characterisation of a Degradable Biotinylated Polylactic acid-Polyethylene Glycol Copolymer. Biomacromolecules. SUM 2001, 2, 575-580. [LA]



Blog Postings

3. AAPS Blog: Nanoparticles in Vaccine Delivery. 2015

2. AAPS Blog: A Vaccine for Dust Mite Allergy-Induced Asthma Attacks. 2014

1. AAPS Blog: Biodegradable Particles: The Future of Vaccine Delivery. 2013



Patents and Technologies 

Granted Patents

  1. A.K. Salem, G.J. Weiner, V, Joshi, A. Makkouk. Methods for treating tumors in situ including intratumor injection of cytotoxic particles and immune checkpoint blockade therapy. US 10314854 B2 (2019) 
  2. S. Elangovan, S. R.R. D'mello, A.T. Do, L.Hong, B. Khorsand-Sourkohi, A.K. Salem. RNA based biomaterial for tissue engineering applications US 10335498 B2 (2019).
  3. L. Hong, B. Amendt, T. Sharp, A.K. Salem. MicroRNA-200 Based Approaches for Modulating Bone Formation Inhibition and Bone Regeneration. US 10, 273, 476 B2 (2019) 
  4. A.K. Salem, S. Geary, G. Weiner, C. Lemke, Y. Krishnamachari. Biodegradable Particulate Formulations. US 9.572,894 B2 (2017). 
  5. J. Yoo, D. Kuruvilla, A.K. Salem, N. Bowden. New Biodegradable Polymers With Sulfenamide Bonds for Drug Delivery Applications US 9,345,776 (2016)
  6. L. Hong, Brad A. Amendt, A.K. Salem, S. Elangovan, G. Avila Ortiz, T. Sharp.  Methods to prevent or treat periodontitis or peri-implantitis. US 10669543 B2 (2016). 
  7. M.E. Anderson, M.A. Joiner, A.K. Salem, A. Wongrakpanich, F.E. Domann, D.D. Hall, O.M. Koval, D.R. Spitz. Mitochondrial-targeted cationic nanoparticles comprising CaMKII inhibitors and uses thereof for treating and preventing diseases and disorders associated with CaMKII activity. US 9168307 B2 (2015)
  8. K.M. Shakesheff and A.K. Salem. Porous Matrix Composed of Crosslinked Particles (Tissue Scaffold). US7785617 B2 (2010) 
  9. A.K. Salem, K.W. Leong and P.C Searson. Methods and Products for Delivering Biological Molecules to Cells using Multicomponent Nanostructures. US7344887B2 (2008) 


Patent Pending:


Mek1/2 Inhibitor-Loaded Microparticle Formulation

US 2021/0361578 A1 

Inventors: Salem Aliasger K, Felder Robert , Ibrahim Youssef Wahib Naguib


Gper Proteolytic Targeting Chimeras

WO 2021/217036 A1 

Inventors: Salem Aliasger K, Filardo Edward J , Lu Anh S , Rouhimoghadam Milad


Implants to Induce Bone Regeneration and Uses Thereof

WO 2020/018818 A1/ US 2021/0308326 A1 

Inventors: Salem Aliasger, Sourkohi Behnoush Khorsand , Femino John E , Fredericks Douglas


Formulation for Delivery of Lubricin Gene

WO 2021/086973 A2 

Inventors: Salem Aliasger K, Martin James A , Chakka Leela Raghava Jaidev , Quarterman Juliana , Zheng Hongjun


Poly(diaminosulfide) Particle-Based Vaccine

US 2021/0379172 A1 

Inventors: Salem Aliasger K, Wafa Emad I , Geary Sean M , Bowden Ned B , Wilson-Welder Jennifer H , Alt David P


Jnk Inhibitors as Anticancer Agents

WO 2020/263989 A1 

Inventors: Salem Aliasger K, Abdelrahman Somaya Ali Mohammed Elsaid


Synthetically Lethal Nanoparticles for Treatment of Cancers

WO 2019/104042 A1/ US 2020/0390717 A1 

Inventors: Salem Aliasger K , Thiel Kristina , Leslie Kimberly , Ebeid Kareem


Nanoparticles Comprising Quinone W Methides and Compositions for Use

WO 2020/257658 A1 

Inventors: Salem Aliasger K, Leslie Kimberly , Meng Xiangbing , Bi Jianling , Ebeid Kareem , Areecheewakul Sudartip


Composition Comprising an Anti-Oxidant to Preserve Corneal Tissue

WO 2020/180985 A1 /CA 3132533 A1 

Inventors: Salem Aliasger K, Ibrahim Youssef Wahib Naguib , Abdelrahman Somaya Ali Mohammed Elsaid , Skeie Jessica M , Aldrich Benjamin T , Schmidt Gregory , Reed Cynthia R , Greiner Mark A , Nishimura Darryl Y , Saha Sanjib


Optoelectronic Cartridge for Cancer Biomarker Detection Utilizing Silicon Nanowire Arrays

US 2019/0011384 A1 

Inventors: Black Marcie R , Toor Fatima , Salem Aliasger



Cationic CaMKII inhibiting nanoparticles for the treatment of allergic asthma

WO 2018/031771 A1 

Inventors: Salem Aliasger K, Grumbach Isabella , Thorn Angie Sue , Paschke John Daryl , Sebag Sara Carolyn


Methods for the Regeneration of Articular Cartilage in Vivo

US 2018/0000736 A1 

Inventors: Martin James A , Yu Yin , Seol Dong Rim , Salem Aliasger K , Sourkohi Behnoush Khorsand , Do Anh-vu T , Brouillette Marc



Methods for the Regeneration of Articular Cartilage in Vivo

WO 2016/112176 A1/CN 107405388/ EP 3250223 A1

Inventors: Martin James A , Yu Yin , Seol Dong Rim , Salem Aliasger K, Sourkohi Behnoush Khorsand , Do Anh-vu T , Brouillette Marc



Bioprinter and Methods of Using Same

WO 2015/066705 A1/ EP 3065875 A1/ US 2016/0288414 A1 

Inventors: Zavazava Nicholas , Zhang Yahui , Yu Yin , Ozbolat Ibrahim T , Hong Liu , Chen Howard , Salem Aliasger K, Moncal Kazim Kermin , Akkouch Adil



Self-Assembly of a Cell-Microparticle Hybrid

US 2010/0190257 A1 

Inventors: Salem Aliasger K, Krishnamachari Yogita


Bioactive Sutures for the Treatment of Cancer

WO 2009/097545 A1 

Inventors: Sandler Anthony D , Weiner George , Salem Aliasger K


Polymer-based delivery system for immunotherapy of cancer

US 2007/0081972 A1 

Inventors: Sandler Anthony D , Salem Aliasger K


Rapid Localized Cell Trapping on Biodegradable Polymers

US 2007/0259382 A1

Inventors: Salem Aliasger K