Citation Indices

Pubmed

Google Scholar (E and OE)

Web of Science

 

Publications

[CA = Corresponding Author][LA = Lead Author][IF = 2014/15 Impact Factor][BC = Book Chapter][R = Review/Editorial/Opinion] - E and OE .

 

2019

163 .E.I. Wafa, S.M. Geary, K. Ross, B. Narasimhan, A.K. Salem. Pentaerythritol-based lipid A bolsters the antitumor efficacy of a polyanhydride particle-based cancer vaccine. Nanomedicine: Nanotechnology, Biology, and Medicine. 2019.  [CA][IF = 6.5]

162. T.M. Acri#, K. Shin#, D. Seol, N.Z. Laird, I. Song, S.M. Geary, J.L. Chakka, J. Martin, A.K. Salem. Tissue engineering for the temporomandibular joint. Advanced Healthcare Materials. 2019. [IF = 5.609][CA][LA]

161. A. Do, R. Smith, P. Tobias, D. Carlsen, E. Pham, N.B. Bowden and A.K. Salem. Sustained Release of Hydrogen Sulfide (H2S) from Poly(lactic acid) Functionalized 4-hydroxythiobenzamide Microparticles to Protect against Oxidative Damage. Annals of Biomedical Engineering. 2019.  [CA][IF = 2.887]

160. J. Bi, S. Areecheewakul, Y. Li, S. Yang, Y. Zhang, K. Ebeid, L. Li , K. Thiel, J. Zhang, A.K. Salem, K.K. Leslie,  X. Meng. MTDH increase cisplatin resistance in cancer by associating with mRNAs of FANCD2 and FANCI. Gynecologic Oncology. 2019[IF =4.54]

159. T.M. Acri, N.Z. Laird, S.M. Geary, J.Chakka, A.K. Salem, K. Shin. Effects of calcium concentration on non-viral gene delivery to bone marrow-derived stem cells. Journal of Tissue Engineering and Regenerative Medicine. 2019. [CA] [IF =3.319]

158. K. Atluri, M.J. Brouillette, D. Seol, B. Khorsand, E. Sander, A.K. Salem, D. Fredericks, E. Petersen, S. Smith, T.P. Fowler, J.A. Martin. Sulfasalazine Resolves Joint Stiffness in a Rabbit Model of Arthrofibrosis. Journal of Orthopedic Research. 2019. [IF =3.14]

157. K.K. Ahmed, M.A. Tamer, M.M. Ghareeb, A.K. Salem.  Recent Advances in Polymeric Implants. AAPS PharmSciTech. 2019. [IF =2.45]

156. L. Amaral-Machado, W. Oliveira, E. Alencar, A.K. Cruz, H.A. Rocha, K. Ebeid, A.K. Salem, E. S.Egito. Bullfrog oil (Rana catesbeiana Shaw) induces apoptosis, in A2058 human melanoma cells by mitochondrial dysfunction triggered by oxidative stress. Biomedicine & Pharmacotherapy. 2019.

155. L. Hong, A. Akkouch, M. Zhu, M.R. Bustillos, S. Eliason, F. Qian, A.K. Salem, B.A. Amendt. MicroRNA-200c Attenuates Periodontitis by Modulating Proinflammatory and Osteoclastogenic Mediators. Stem Cells and Development. 2019

154. J. L. Chakka, A.K. Salem. 3D Printing in Drug Delivery Systems. Journal of 3D Printing in Medicine. 2019. [CA][R]

153. S.O. Suliman, E.I. Wafa, S.M. Geary, A.K. Salem. Polymeric particles as cancer vaccine vectors. American Pharmaceutical Review. 2019 [CA][R]

152. T.L. Terry, B.E. Givens, V.G.J. Rodgers, A.K. Salem. Tunable properties of poly-DL-lactide-monomethoxypolyethylene glycol porous microparticles for sustained release of polyethylenimine-DNA polyplexes. AAPS PharmSciTech. 2019. [CA]

151. J.C. Quarterman, B.E. Givens, S.M. Geary, A.K. Salem. Drug Eluting Degradable Coatings on Biomedical Implants. Book Chapter in “Emerging Technologies for Biofabrication and Biomanufacturing”. (2019) Edited by El Assal, Chen and Demirci [CA][BC]

150. A.K. Salem. Higher Education Institutions as a Fertile Environment for Inter-Disciplinary Research that Can Solve Complex Biological Problems. As Far as the Eye Can See: The Promises and Perils of Research and Scholarship in the 21st Century. 2019. (Edited by D. Reed; University of Iowa Press) [BC][LA][CA]

 

2018

149. K. Ebeid, X. Meng, K.W. Thiel, A. Do, S.M. Geary, A. S. Morris, E.L. Pham, A. Wongrakpanich, Y.S. Chhonker, D.J. Murry, K.K. Leslie, A.K. Salem. Synthetically Lethal Nanoparticles for Treatment of Endometrial Cancer. Nature Nanotechnology. 2018. [CA][IF = 38.99] 

148. M.C. Coleman, J.E. Goetz, M.J. Brouillette, D. Seol, M.C. Willey, E.B. Petersen, B. Khorsand, A.S. Morris, A.K. Salem, D.C. Fredericks, T.O. McKinley, J.A. Martin. Mitochondrial Responses to Intraarticular Fracture are a Disease-Modifying Target for Posttraumatic Osteoarthritis Prevention. Science Translational Medicine. 2018. [IF = 16.976] 

147. E.I. Wafa, S.M. Geary, K.A. Ross, J.T. Goodman, B. Narasimhan, A.K. Salem. A single shot of a polyanhydride particle-based vaccine generates potent antigen-specific anti-tumor immune responses in vivo. Journal of Pharmacology and Experimental Therapeutics. 2018. [CA][IF = 3.867]

146. J. Carter, E. Brown, J. Grace, A.K. Salem, E.E. Irish, N. Bowden Improved growth of pea, lettuce, and radish plants using the slow release of hydrogen sulfide from GYY-4137. PLoS One. 2018.

145. K.S. Worthington, A. Do, B.A. Tucker and A.K. Salem. Two-Photon Polymerization as a Tool for Studying 3D Printed Topography-Induced Stem Cell Fate. Macromolecular Biosciences. 2018. [CA][IF = 3.392]

144. T. Kruger, B.E. Givens, T. Lansakara, K. Bell, H. Mohapatra, A.K. Salem, A. Tivanski, L. Stevens. Mechanosensitive endocytosis of high-stiffness, sub-micron microgels in macrophage and hepatocarcinoma cell lines. ACS Applied Bio Materials. 2018.

143. B. Khorsand#, S. Elangovan#, L. Hong, M. Kormann, A.K. Salem. A Bioactive Collagen Membrane that Enhances Bone Regeneration. Journal of Biomedical Materials Research. 2018.

142. R. Smith, W. Duan, J. Quaterman, A. Morris, C. Collie, M. Black, F. Toor,  A.K. Salem. Surface Modifying Doped Silicon Nanowire based Solar Cells for Applications in Bio-sensing. Advanced Technological Materials. 2018. [CA][IF = 4.662]

141. A. Do, K.S. Worthington, B.A. Tucker and A.K. Salem. Controlled Drug Delivery from 3D Printed Two-Photon Polymerized Poly(Ethylene Glycol) Dimethacrylate Devices. International Journal of Pharmaceutics. 2018. [CA][IF = 3.994]

140. B.E. Givens, Y.W. Naguib, S.M. Geary, E.J. Devor, A.K. Salem. Nanoparticle-based delivery of CRISPR/Cas9 genome editing therapeutics. The AAPS Journal. 2018. [CA][IF = 3.819]

139. A. Do, S.M. Geary, D. Seol, P. Tobias, D. Carlsen, N. Leelakanok, J.A. Martin, A.K. Salem. Combining Ultrasound and Intratumoral Administration of Doxorubicin-loaded Microspheres to Enhance Tumor Cell Killing. International Journal of Pharmaceutics. 2018. [CA][IF = 3.994] 

138. Nanoparticle-Based CpG-ODN Therapy for Treating Allergic Asthma. Brittany E. Givens, Sean M. Geary and Aliasger K. Salem. Immunotherapy. 2018. [CA][IF = 2.070] 

137. N. Leelakanok, S.M. Geary, A.K. Salem. Fabrication and Use of PLGA-based Formulations Designed for Modified Release of 5-Fluorouracil. Journal of Pharmaceutical Sciences. 2018. [CA][IF = 2.59]

136. N. Leelakanok, S.M. Geary, A.K. Salem. Antitumor Efficacy and Toxicity of 5-FU-loaded PLGA Pellets. Journal of Pharmaceutical Sciences. 2018. [CA][IF = 2.59]

135. A. Do, R. Smith, T.M. Acri, S.M. Geary, A.K. Salem. 3D Printing Technologies for 3D Scaffold Engineering. Book Chapter in “Functional three-dimensional tissue engineering scaffolds: Technologies and applications”, Edited by Deng and Kuiper (Elsevier). [CA][BC]

 

2017

 

134. B. Khorsand, N. Nicholson, A. Do, J.E. Femino, J.A. Martin, E. Petersen, B. Guetschow, D.C. Fredericks, A.K. Salem. Regeneration of bone using synergistic FGF2 and BMP2 gene delivery in a diaphyseal long bone radial defect diabetic rabbit model. Journal of Controlled Release. 2017. [CA][IF = 7.705]

133.  K.K. Ahmed, S.M. Geary, and A.K. Salem. Surface engineering tumor cells with adjuvant-loaded particles for use as cancer vaccines. Journal of Controlled Release. 2017. [CA][IF = 7.705]

132. A. Schumacher, C. Gilmer, K. Atluri, A. Jugessur, A.K. Salem, N. Bowden, M.L. Raghavan, D. Hasan. Development and Evaluation of a Nanometer-Scale Hemocompatible and Antithrombotic Coating Technology for Commercially Available Intracranial Stents and Flow Diverters. ACS Applied Nanomaterials. 2017.

131. K. Shin, T. Acri, S.M. Geary, A.K. Salem. Biomimetic Mineralization of Biomaterials Using Simulated Body Fluids (SBFs) for Bone Tissue Engineering and Regenerative Medicine. Tissue Engineering Part A. 2017. [CA][IF = 3.892]

130. A.S. Morris, S.C. Sebag, J.D. Paschke, A. Wongrakpanich, K. Ebeid, M.E. Anderson, I.M. Grumbach and A.K. Salem. Cationic CaMKII Inhibiting Nanoparticles Prevent Allergic Asthma. Molecular Pharmaceutics. 2017. [CA][IF = 4.342]

129. J. Srivastava, C.L Robertson, K. Ebeid, M. Dozmorov, D. Rajasekaran, R. Mendoza, A. Siddiq, M.A. Akiel, N. Jariwala, X. Shen, J.J. Windlw, M.A. Subler, N.D. Mukhopadhyay, S. Giashuddin, S. Ghosh, Z. Lai, Y. Chen, P.B. Fisher, A.K. Salem, A. Sanyal, D. Sarkar. A Novel Role of Astrocyte Elevated Gene-1 (AEG-1) in Regulating Non-alcoholic Steatohepatitis (NASH). Hepatology. 2017.  [CA][IF = 11.055]

128. A. Wongrakpanich, A.S. Morris, S.M. Geary, M.L. Joiner, A.K. Salem. Surface-modified particles loaded with CaMKII inhibitor protect cardiac cells against mitochondrial injury. International Journal of Pharmaceutics. 2017. [CA][IF = 3.994]

127. E.I. Wafa, S.M. Geary, J.T. Goodman, B. Narasimhan, A.K. Salem. The Effect of Polyanhydride Chemistry in Particle-based Cancer Vaccines on the Magnitude of the Antitumor Immune Response. Acta Biomaterialia. 2017. [CA][IF = 6.025]

126. A.S. Morris, A.K. Salem. Surface Engineered Nanoparticles: Considerations for Biomedical Applications. Advanced Engineering Materials. 2017. [R][CA]

125. A.K. Salem. Recent Advances in Musculoskeletal Tissue Regeneration. The AAPS Journal. 2017. [R][LA][CA][IF = 3.819]

124. S. D'Mello#, K. Atluri#, S.M Geary, L. Hong, S. Elangovan, A.K. Salem. Bone Regeneration using Gene-Activated Matrices. The AAPS Journal. 2016 #Joint First Authors [CA][R][IF = 3.819]

123. K. Ebeid, H. Giang, A.K. Salem. A HPLC-UV Method for Simultaneous Determination of MK-1775 and AZD-7762 in both Acetonitrile-Aqueous Solution and Mouse Plasma. Journal of Chromatography B. 2017. [CA][IF = 2.68]

122. B. Khorsand, S. Elangovan, L.Hong, A. Dewerth, M. Kormann, A.K. Salem. A comparative study of the bone regenerative effect of chemically modified RNA encoding BMP-2 or BMP-9. The AAPS Journal. 2017. [CA][IF = 3.819]

 

2016

 

121.  A.B. Plonka, B. Khorsand, N. Yu, J.V. Sugai, A.K. Salem, W.V. Giannobile, S. Elangovan. Effect of Sustained PDGF Non-Viral Gene Delivery on Repair of Tooth-Supporting Bone Defects.  Gene Therapy. 2016 [IF = 3.242]

120. T. Sharp, B. Khorsand, C. Fischer, S. Eliason , A.K. Salem, K. Brogden, B. Amendt, L. Hong. MicroRNA-200c directly targets and represses IL-6, IL-8, and CCL-5 expression and enhances osteogenic differentiation. PLoS One. 2016. [IF = 3.057]

119. K.S. Worthington, B.J. Green, M. Rethwisch, L.A. Wiley, B.A. Tucker, and C.A.Guymon and A.K. Salem. Neuronal Differentiation of Induced Pluripotent Stem Cells on Surfactant Templated Chitosan Hydrogels. Biomacromolecules. 2016. [CA][IF = 5.75]

118. A. Do, A. Akkouch, B. Green, S.M. Geary, I. Ozbolat, A.K. Salem. Controlled and Sequential Delivery of Fluorophores from 3D Printed Alginate-PLGA Tubes. Annals of Biomedical Engineering. 2016. [CA][IF = 2.887]

117. S.M. Geary, A.S. Morris and A.K. Salem. Assessing the Impact of Engineered Nanomaterials on the Environment and Human Health. Journal of Allergy and Clinical Immunology. 2016. [CA][R][IF = 12.485]

116. K. Atluri, J. Lee, D. Seabold, S. Elangovan, A.K. Salem. Gene Activated Titanium Surfaces Promote In Vitro Osteogenesis. The International Journal of Oral & Maxillofacial Implants. 2016. [CA][IF = 1.451]

115. A. Wongrakpanich, I.A. Mudunkotuwa, S.M. Geary, A.S. Morris, K.A. Mapuskar, D.R. Spitz, V.H. Grassian and A.K. Salem. Size-dependent cytotoxicity of copper oxide nanoparticles in lung epithelial cells. Environmental Science: Nano. 2016. [CA][IF = 5.896]

114. K. Atluri, A. De Jesus, S. Chinnathambi, M. Brouillette, J. Martin, A.K. Salem*, E. Sander*. Blebbistatin-Loaded Poly(D,L lactide-co-glycolide) Particles for Treating Arthrofibrosis. ACS Biomaterials Science & Engineering. 2016. [CA][IF = pending]

113. S. Elangovan, M.S.D. Kormann, B. Khorsand, A.K. Salem.  The Oral and Craniofacial Relevance of Chemically Modified RNA Therapeutics. Discovery Medicine. 2016. [CA][R][IF = 3.426]

112. K.S. Worthington, L.A. Wiley, A. Guymon, A.K. Salem and B.A. Tucker. Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous PLGA Scaffolds.  Journal of Ocular Pharmacology and Therapeutics. 2016. [CA][IF = 1.754 ]

111. K. Ahmed, S.M. Geary, A.K. Salem. Development and Evaluation of Biodegradable Particles Co-loaded with Antigen and the Toll-like Receptor Agonist, Pentaerythritol Lipid A, as a Cancer Vaccine. Journal of Pharmaceutical Sciences. 2016. [CA][IF = 2.59]

110. Nanotoxicity. A.S. Morris, A.K. Salem. Nanomedicine for Inflammatory Diseases.  (CRS Press, Taylor and Francis; Ed: L. Milane, M. Amiji). 2016. [CA][BC]

109. Production of adjuvant-loaded biodegradable particles for use in cancer vaccines. C.M. de Barros, E.I. Wafa, K. Chitphet, K. Ahmed, S.M. Geary, A.K. Salem. Vaccine Adjuvants: Methods and Protocols (Springer; Ed: C.B. Fox). 2016. [CA][BC]

 

2015

 


108. A.S. Morris, A. Adamcakova-Dodd, S.E. Lehman, A. Wongrakpanich, P.S. Thorne, S.C. Larsen, A.K. Salem. Amine Modification of Nonporous Silica Nanoparticles Reduces Inflammatory Response Following Intratracheal Instillation in Murine Lungs. Toxicology Letters. 2015. [CA][IF = 3.262]

107. S.E. Lehman, A.S. Morris, P.S. Mueller, A.K. Salem, V.H. Grassian, S.C. Larsen. Silica Nanoparticle-Generated ROS as a Predictor of Cellular Toxicity: Mechanistic Insights and Safety by Design. Environmental Science: Nano. 2015. [IF = 5.896]

106. S. Elangovan*, B. Khorsand*, A. Do, L. Hong, A. Dewerth, M. Kormann, R.D. Ross, D.R. Sumner, C. Allamargot, and A.K. Salem. Chemically modified RNA activated matrix induced bone regeneration. Journal of Controlled Release. 2015. [CA][IF = 7.705]

105. N. Leelakanok, C.L Fischer, A.M. Bates, J.M. Guthmiller, G.K. Johnson, A.K. Salem, K.A. Brogden, N. Brogden Cytotoxicity of HBD3 for dendritic cells, normal human epidermal keratinocytes, hTERT keratinocytes, and primary oral gingival epithelial keratinocytes in cell culture conditions. Toxicology Letters. 2015. [CA][IF = 3.262]

104. S.R. D’Mello, S. Elangovan, A.K. Salem. FGF2 Gene Activated Matrices Promote Proliferation of Bone Marrow Stromal Cells. Archives of Oral Biology. 2015. [CA][IF = 1.549]

103. S.M. Geary, Q. Hu, V.B. Joshi, N.B. Bowden, A.K. Salem. Diaminosulfide based polymer microparticles as cancer vaccine delivery systems.  Journal of Controlled Release. 2015. [CA][IF = 7.705]

102. T.S. Long, A. Wongrakpanich, A. Do, A.K. Salem, N.B. Bowden. Long-term release of a thiobenzamide from a backbone functionalized poly(lactic acid). Polymer Chemistry. 2015. [IF = 5.687]

101. K.A. Ross, T.M. Brenza, A. Binnebose, Y. Phanse, A. Kanthasamy, H.Gendelman, A.K. Salem, L. Bartholomay, B. Bellaire, B. Narasimhan. Nano-enabled Delivery of Diverse Payloads across Complex Biological Barriers. Journal of Controlled Release. 2015. [R][IF = 7.705]

100. A. Wongrakpanich, M. Wu and A.K. Salem. Correlating Intracellular Non-viral Polyplex Localization with Transfection Efficiency using High-Content Screening. Biotechnology Progress. 2015. [CA] [IF = 2.167]

99. K. Atluri, D. Seabold, L. Hong, S. Elangovan, A.K. Salem. Nanoplex-Mediated Co-delivery of Fibroblast Growth Factor and Bone Morphogenetic Protein Genes Promotes Osteogenesis in Human Adipocyte-Derived Mesenchymal Stem Cells. Molecular Pharmaceutics. 2015. [CA][IF = 4.342]

98. D. Rajasekaran#, J. Srivastava#, K. Ebeid#, R. Gredler, M. Akiel, N. Jariwala, C. L. Robertson, X. Shen, A. Siddiq, P.B. Fisher, A.K. Salem*, D. Sarkar*. Combination of nanoparticle-delivered siRNA for Astrocyte elevated gene-1 (AEG-1) and all-trans retinoic acid (ATRA): an effective therapeutic strategy for hepatocellular carcinoma (HCC). Bioconjugate Chemistry. 2015 #Joint First Authors *Corresponding Authors. [CA][IF = 4.500]

97. A. Do, B. Khorsand, S.M. Geary, A.K. Salem. 3D Printing of Scaffolds for Tissue Regeneration Applications. Advanced Healthcare Materials. 2015. [CA][R][IF = 5.79]

96. M. Flores, C. Chew, K. Tyan, W.Q. Huang, A.K. Salem and R. Clynes. FcγRIIB Prevents Inflammatory Type I IFN Production from Plasmacytoid Dendritic Cells during a Viral Memory Response. Journal of Immunology. 2015. [IF = 4.92]

95. A. Makkouk, V.B Joshi, C.D. Lemke, A. Wongrakpanich, A.K Olivier, S.E. Blackwell, A.K. Salem, G.J. Weiner. Three Steps to Breaking Tolerance to Lymphoma: A Microparticle Approach. Cancer Immunology Research. 2015. [IF = 3.57]

94. A. Makkouk, V.B. Joshi, A. Wongrakpanich, C.D. Lemke, B.P. Gross, A.K. Salem, G.J. Weiner. Biodegradable Microparticles Loaded with Doxorubicin and CpG for In Situ Immunization Against Tumors. The AAPS Journal. 2015. [IF = 3.819]

93. A.K. Salem. Nanoparticles in Vaccine Delivery. The AAPS Journal. 2015. [CA][R][IF = 3.819]

92. S.R. D’Mello, S. Elangovan, L. Hong, R.D. Ross, D.R. Sumner, and A.K. Salem. A Pilot Study Evaluating Combinatorial and Simultaneous Delivery of Polyethylenimine-Plasmid DNA Complexes Encoding for VEGF and PDGF for Bone Regeneration in Calvarial Bone Defects. Current Pharmaceutical Biotechnology. 2015. [CA][IF = 2.511]

91. V.B. Joshi, A.A. Dodd, X. Jing, A. Wongrakpanich, K. Gibson-Corley, P.S. Thorne and A.K. Salem. Development of a poly (lactic-co-glycolic acid) particle vaccine to protect against house dust mite induced allergy. The AAPS Journal. 2014. [CA][IF = 3.819]

90. S.R. D’Mello, S. Elangovan, L. Hong, R.D. Ross, D.R. Sumner, and A.K. Salem. Incorporation of copper into chitosan scaffolds promotes bone regeneration in rat calvarial defects. Journal of Biomedical Materials Research: Part B - Applied Biomaterials. 2015. [CA][IF = 2.881]

89. A.S. Morris, A. Wongrakpanich, S.M. Geary, A.K. Salem. Microparticles and Nanoparticles for Cancer Targeting Vaccines. Book Chapter in “Micro and Nanotechnology in Vaccine Development, 1st edition by Skwarczynski & Toth (Elsevier). [CA][BC]

 

2014

 

88. S.M. Geary and A.K. Salem. Exploiting the tumor phenotype using biodegradable submicron carriers of chemotherapeutic drugs. Critical Reviews in Oncogenesis. 2014. [CA][R][IF = pending]

87. K.K. Ahmed, S.M. Geary and A.K. Salem. Applying biodegradable particles to enhance cancer vaccine efficacy. Immunologic Research. 2014. [CA][R][IF = 2.934]

86. A. Wongrakpanich, A.A. Dodd, W. Xie, V.B. Joshi,  K.A. Mapuskar, D.R. Spitz, P.S. Thorne and A.K. Salem. The Absence of CpG in Plasmid DNA-Chitosan Polyplexes Enhances Transfection Efficiencies and Reduces Inflammatory Responses in Murine Lungs. Molecular Pharmaceutics. 2014. [CA][IF = 4.342]

85. B.P. Gross, A. Wongrakpanich, M.B. Francis, A.K. Salem, and L.A. Norian. Therapeutic microparticle-based tumor lysate vaccine reduces spontaneous metastasis in murine breast cancer. The AAPS Journal. 2014. [IF = 3.819]

84. A.K. Salem. A promising CpG adjuvant loaded nanoparticle based vaccine for treatment of dust mite allergies. Immunotherapy. 2014. [CA][R][IF = 2.070]

83. K.S. Worthington, L.A. Wiley, A.M. Bartlett; E.M. Stone, R.F. Mullins, A.K. Salem, A. Guymon, B.A Tucker.  Mechanical Properties of Murine and Porcine Ocular Tissues in Compression. Experimental Eye Research. 2014. [IF = 2.998]

82. A. Wongrakpanich, S.M. Geary, M.A. Joiner, M.E. Anderson, A.K. Salem. Mitochondria-targeting particles. Nanomedicine. 2014. [CA][R][IF = 3.573]

81. S. Elangovan, S.R. D’Mello, L. Hong, R.D. Ross, C. Allamargot, D.V. Dawson, C.M. Stanford, G.K. Johnson, D.R. Sumner, and A.K. Salem. The Enhancement of Bone Regeneration by Gene Activated Matrix Encoding for Platelet Derived Growth Factor. Biomaterials. 2014. [CA][IF = 8.387]

80. S. D’Mello, A.K. Salem, L. Hong, and S. Elangovan. Characterization and Evaluation of the Efficacy of Cationic Complex Mediated Plasmid DNA Delivery in Human Embryonic Palatal Mesenchyme Cells. Journal of Tissue Engineering and Regenerative Medicine. 2014. [CA][IF = 4.71]

79. A.K. Salem. Recent progress on the development of gene activated scaffolds encoding platelet derived growth factor for enhanced bone regeneration. Regenerative Medicine. 2014. [CA][R][IF = 2.602]

78. S.M. Geary, A.K. Salem. Vaccines. Encyclopedia of Cancer and Society, Second Edition. Edited by Graham A. Colditz and J. Geoffrey Golson. 2014. [CA][BC]

77. A. Do, B. Khorsand, S.M. Geary, A.K. Salem. Melanoma. Encyclopedia of Cancer and Society, Second Edition. Edited by Graham A. Colditz and J. Geoffrey Golson. 2014. [CA][BC]

76. K. Ahmed, A. Al-Jumaili, S.M. Geary, A.K. Salem. Cancer in Iraq. Encyclopedia of Cancer and Society, Second Edition. Edited by Graham A. Colditz and J. Geoffrey Golson. 2014. [CA][BC]

75. A.K. Salem. Holden Comprehensive Cancer Center at The University of Iowa. Encyclopedia of Cancer and Society, Second Edition. Edited by Graham A. Colditz and J. Geoffrey Golson. 2014. [LA CA][BC]

 

2013

 


74. S.M. Geary, C.D. Lemke, D.M. Lubaroff, A.K. Salem. Proposed mechanisms of action for prostate cancer vaccines. Nature Reviews Urology. 2013. [CA][R][IF = 5.957]

73. C.D. Lemke, S.M. Geary, V.B. Joshi, A.K. Salem. Antigen coated poly α-hydroxy acid based microparticles for heterologous prime-boost adenovirus based vaccinations. Biomaterials. 2013. [CA][IF = 8.387]

72. S.M. Geary, C.D. Lemke, D.M. Lubaroff and A.K. Salem. The combination of a low-dose chemotherapeutic agent, 5-fluorouracil, and an adenoviral tumor vaccine has a synergistic benefit on survival in a model tumor system. PLoS ONE. 2013. [CA][IF = 3.057]

71. K.L.S. Worthington, A.A. Dodd, A.Wongrakpanich, I.A. Mudunkotuwa, K.A. Mapuskar, V.B. Joshi,  C. A.Guymon, D.R. Spitz, V.H. Grassian, P.S. Thorne and A.K. Salem. Chitosan coating of copper nanoparticles reduces in vitro toxicity and increases inflammation in the lung. Nanotechnology. 2013. [CA][IF = 3.573 ]

70. V.B. Joshi, S.M. Geary, B.R. Carrillo-Conde, B. Narasimhan, A.K. Salem. Characterizing the anti-tumor response in mice treated with antigen-loaded polyanhydride microparticles. Acta Biomaterialia. 2013. [CA][IF = 6.025]

69. V.B. Joshi, S.M. Geary, A.K. Salem. Biodegradable particles as vaccine delivery systems: Size matters. The AAPS Journal. 2013. [CA][IF = 3.819]

68. S. D'Mello, J. Yoo, N.B. Bowden, and A.K.  Salem. Microparticles prepared from sulfenamide-based polymers. Journal of Microencapsulation. 2013. [CA][IF = 1.631 ]

67. V.B. Joshi, S.M. Geary, B.P. Gross, A. Wongrakpanich, L.A. Norian, A.K. Salem. Tumor lysate-loaded biodegradable microparticles as cancer vaccines. Expert Review of Vaccines. 2013. [CA][R][IF = 4.217]

66. S.M. Geary, A.K. Salem. Human prostate cancer vaccines - clinical trials update. OncoImmunology. 2013. [CA][R][IF = 6.266]

65. V.B Joshi, S.M. Geary, A.K. Salem. Biodegradable particles as vaccine antigen delivery systems for stimulating cellular immune responses. Human Vaccines & Immunotherapeutics. 2013. [CA][R][IF = 3.643]

64. N. Wei, Y. Yu, V. Joshi, T. Schmidt, F. Qi-an, A.K. Salem, C. Stanford, L. Hong. Glucocorticoid receptor Antagonist and siRNA Prevent Senescence of Human Bone Marrow Mesenchymal Stromal Cells in vitro. Cell and Tissue Research. 2013. [IF = 3.677]

63. K. K. Ahmed, S.M. Geary and A.K. Salem. Invited Book chapter entitled “Engineering the surface of cells using the biotin-avidin interaction” in the Book “Micro- and Nanoengineering of the Cell Surface” (Elsevier). Edited by Weian Zhao (UCI) and Jeffrey Karp (Harvard). [CA][BC]

 

2012

 


62. S. Krishnamurthy, M.A. Behlke, S. Ramchandran, A.K. Salem, P.B. McCray Jr, B.L. Davidson. Manipulation of Cell Physiology Enables Gene Silencing in Well-Differentiated Airway Epithelia. Molecular Therapy - Nucleic Acids. 2012. [IF = 5.048]

61. R.M. Walk, S.T. Elliot, F.C. Blanco, J.A. Snyder, A. Jacobi, S. Rose, M. Behlke, A.K. Salem, S. Vukmanovic, A.D. Sandler. T-cell activation is enhanced by targeting IL-10 cytokine production in toll-like receptor-stimulated macrophages. ImmunoTargets and Therapy. 2012. [IF = 2.363]

60. H.M. Rosevear, Y. Krishnamachari, C.A. Ariza, S.K. Mallapragada, A.K. Salem, T.S. Griffith,  B.R. De Young, M. Wald. Effect of combined locally delivered growth factors and systemic sildenafil citrate on the number of micro-recanals in a biodegradable conduit for reconstruction of the vas deferens. Urology. 2012. [IF = 2.365]

59. J. Yoo, D. Kuruvilla, S.R. D’Mello, A.K. Salem, and N.B. Bowden. New class of biodegradable polymers formed from reactions of an inorganic functional group. Macromolecules. 2012. [IF = 5.554]

58. J. Yoo, S.R. D’Mello, T. Graf, A.K. Salem, and N.B. Bowden. Synthesis of the first poly(diaminosulfide)s and an investigation of their applications as drug delivery vehicles. Macromolecules. 2012. [IF = 5.554]

57. A.K. Salem, S. Patil, D.J. Burgess. Recent progress in non-viral nucleic acids delivery. International Journal of Pharmaceutics. 2012. [CA LA][R][IF = 3.994]

56. L. Hong, N. Wei, V. Joshi, Y. Yu, N. Kim, Y. Krishnamachari, Q. Zhang, A.K. Salem. Effects of glucocorticoid receptor siRNA delivered by poly lactic-co-glycolic acid microparticles on proliferation and differentiation capabilities of human mesenchymal stromal cells. Tissue Engineering, Part A. 2012. [CA][IF = 3.892]

55. A. Wongrakpanich, V.B. Joshi, A.K. Salem. Poly(galactaramidoamine) is an efficient cationic polymeric non-viral vector with low cytotoxicity for transfecting human embryonic kidney (HEK293) and murine macrophage (RAW264.7) cells. Pharmaceutical Development and Technology.  2012. [CA][IF = 1.566]

54. N. Kim, D. Jiang, A. Jacobi, K.A. Lennox, S. Rose, M.A. Behlke, A.K. Salem. Synthesis and characterization of mannosylated pegylated polyethylenimine as a carrier for siRNA. International Journal of Pharmaceutics. 2012. [CA][IF = 3.994]

53. D. Jiang, A.K. Salem. Optimized dextran-polyethylenimine conjugates are efficient non-viral vectors with reduced cytotoxicity when used in serum containing environments. International Journal of Pharmaceutics. 2012. [CA][IF = 3.994]

52. V.B. Joshi, S.M. Geary, A.K. Salem. Production of antigen-loaded nanoparticles and uptake by antigen-presenting cells.  Invited Chapter in the Book entitled ‘Cancer Vaccines Methods and Protocols. Methods in Molecular Biology.  Springer verlag Humana press.  Edited by Michael Lawman. 2012. [CA][BC]

 

2011

 


51. C.D Lemke, J.B. Graham, S.M. Geary, G. Zamba, D.M. Lubaroff, A.K. Salem. Chitosan is a surprising negative modulator of cytotoxic CD8+ T cell responses elicited by adenovirus cancer vaccines. Molecular Pharmaceutics. 2011. [CA][IF = 4.342]

50. S.M. Geary, C.D. Lemke, D.M. Lubaroff, A.K. Salem. Tumor immunotherapy using adenovirus vaccines in combination with intratumoral doses of CpG ODN. Cancer Immunology, Immunotherapy. 2011. [CA][IF = 3.941]

49. D.A. Santillan, K.K. Rai, M.K. Santillan, Y. Krishnamachari, A.K. Salem and S. Hunter. Efficacy of Polymeric Encapsulated C5a peptidase-based Group B Streptococci Vaccines in a Murine Model. American Journal of Obstetrics & Gynecology. 2011. [IF = 4.704]

48. C.D. Lemke, J.B. Graham, D.M. Lubaroff, A.K. Salem. Development of an MHC class I Ld-restricted PSA peptide-loaded tetramer for detection of PSA-specific CD8+ T cells in the mouse. Prostate Cancer and Prostatic Diseases. 2011. [CA][IF = 3.803]

47. J. Intra, X.Q. Zhang, R.L. Williams, X. Zhu, A.D. Sandler, A.K. Salem. Immunostimulatory sutures that treat local disease recurrence following primary tumor resection. Biomedical Materials 2011. [CA][IF = 3.697]

46. L. Hong, Y. Krishnamachari, D. Seabold, V. Joshi, G. Schneider, A.K. Salem. Intracelluar release of 17-β estradiol from cationic polyamidoamine dendrimer surface modified poly lactic-co-glycolic acid microparticles improves osteogenic differentiation of human mesenchymal stromal cells. Tissue Engineering Part C: Methods  Vol 17, Iss 3, 319-325, 2011.  [CA][IF = 3.892 ]

45. Y. Krishnamachari, S.M. Geary, C.D. Lemke, A.K. Salem. Nanoparticle delivery systems in cancer vaccines. Pharmaceutical Research. Vol 28, Iss 2, 215-236, 2011. [CA][R][IF = 3.42]

44. J. Intra, A.K. Salem. Rational design, fabrication, characterization and in vitro testing of biodegradable microparticles that generate targeted and sustained transgene expression in HepG2 liver cells. Journal of Drug Targeting. 2011. [CA][IF = 2.821]

43. A.K. Salem, M. Behlke. siRNA Delivery Vehicles. Pharmaceutical Formulations and Quality. 2011. [CA LA][BC]

42. S.M. Geary, C.D. Lemke, Y. Krishnamachari, A.K. Salem. New nanobiotechnological strategies for the development of vectors for cancer vaccines.  Invited Chapter in the Book entitled ‘Pharmaceutical Biotechnology 2nd Edition‘. Wiley-Blackwell.  Edited by Oliver Kayser and Herbert Warzecha. 2011. [CA][BC]

41. D.J. Kuruvilla and A.K. Salem.  Nanotechnology and nanomedicine in diabetes: an overview. Invited Chapter in the Book entitled ‘Nanotechnology and nanomedicine in diabetes‘. Science Publishers.  Edited by Victor R. Preedy. 2011. [CA][BC]

 

2010

 


40. J. Intra, A.K. Salem. Fabrication, characterization and in vitro evaluation of poly lactic-co-glycolic acid microparticles loaded with polyamidoamine-plasmid DNA dendriplexes for applications in non-viral gene delivery. Journal of Pharmaceutical Sciences Volume: 99   Issue: 1   Pages: 368-384. 2010. [CA][IF = 2.59]

39. A.K. Salem, M. Behlke. siRNA Delivery Vehicles. Invited Chapter in the Book entitled "RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development". John Wiley & Sons Inc. Edited by Paul H. Johnson. 2010. [LA CA][BC]

38. A. Petushkov, N. Ndiege, A.K. Salem, S.C. Larsen. Toxicity of Silica Nanomaterials: Zeolites, Mesoporous Silica, and Amorphous Silica Nanoparticles. Advances in Molecular Toxicology V4. 2010. [CA][BC]

 

2009

 


37. A. Petushkov, J. Intra, J.B. Graham, S.C. Larsen, A.K.Salem. Effect of Crystal Size and Surface Functionalization on the Cytotoxicity of Silicalite-1 Nanoparticles. Chemical Research in Toxicology. Volume: 22   Issue: 7   Pages: 1359-1368. 2009. [CA][IF = 3.025]

36. R. Goforth, A.K. Salem, X. Zhu, S. Miles, X.Q. Zhang, J. Lee, A.D. Sandler. Immune Stimulatory Antigen Loaded Particles Combined with Depletion of Regulatory T-cells Induce Potent Tumor Specific Immunity in a Mouse Model of Melanoma. Cancer Immunology, Immunotherapy 58 (4) 517-30 Apr 2009. [IF = 3.941]

35. A.K. Salem and G.J. Weiner. CpG Oligonucleotides as Immunotherapeutic Adjuvants: Innovative Applications and Delivery Strategies. Advanced Drug Delivery Reviews. 61 (2009) 193-194. [CA LA][R][IF = 15.606]

34. Y. Krishnamachari and A.K. Salem. Innovative Strategies for Co-delivering Antigens and CpG Oligonucleotides. Advanced Drug Delivery Reviews. 61 (2009) 205-217. [CA][R][IF = 15.606]

 

2008

 

33. J. Intra, A.K. Salem. Characterization of the Transgene Expression Generated by Branched and Linear Polyethylenimine (PEI)-Plasmid DNA Nanoparticles In Vitro and After Intraperitoneal Injection In Vivo. Journal of Controlled Release. (130) 129-138 2008. [CA][IF = 7.705]

32. M. Pearce, B. Mai, N. Lee. S.C. Larsen, A.K. Salem. Silicalite Nanoparticles that Promote Transgene Expression. Nanotechnology (19) 17 Article Number: 175103 2008. [CA][IF = 3.573]

31. J. Intra, J.M Glasgow, H. Q. Mai, A.K. Salem. Pulsatile Release of Biomolecules from Polydimethylsiloxane (PDMS) Chips with Hydrolytically Degradable Seals. Journal of Controlled Release (127) 280-287. 2008. [CA][IF =7.705 ]

30. J.D. Clapper, M.E. Pearce, C.A. Guymon, A.K. Salem. Biotinylated Biodegradable Nanotemplated Hydrogel Networks for Cell Interactive Applications. Biomacromolecules  (9) 1188-1194. 2008. [CA][IF = 5.75]

29. Y. Krishnamachari, M.E. Pearce, A.K. Salem. Self-assembly of Cell-Microparticle Hybrids. Advanced Materials. (20) 5 989-993. 2008. [CA][IF = 17.49 ]

28. A. O. Abbas, M.D. Donovan, A.K. Salem. Formulating PLGA Particles for Plasmid DNA Delivery. Journal of Pharmaceutical Sciences. 97(7): 2448-61.July. 2008.  [CA][R][IF = 2.59]

27. X.Q. Zhang, J. Intra, A.K. Salem. Comparative Study of Poly (lactic-co-glycolic acid)-Poly Ethyleneimine-Plasmid DNA Microparticles Prepared Using Double Emulsion Methods. Journal of Microencapsulation. (25) 1-13. 2008. [CA][IF = 1.631]

26. J.B. Graham, M.E. Pearce, A.K. Salem. Multifunctional, Spherical & Anisotropic Metal and Metal Oxide Nanomaterials in Medical Diagnosis and Therapy. Invited Chapter in "Nanomaterials for the Life Sciences – Volume 3". Wiley-VCH. Edited by Challa Kumar. 2008. [CA][BC]

25. Y. Krishnamachari, A.K. Salem. Nano-Bio Polymers and Composites. Invited chapter in "Nano-and Biocomposites". Taylor & Francis/CRC Press 2008. Edited by Lau and Hussain. [CA][BC]

24. J. Glasgow, A.K. Salem. Stem Cells and Cancer. Invited review for Encyclopedia of Stem Cell Research. Sage Publications. Edited by Clive Niels Svendsen, Ph.D., Allison D. Ebert, Ph.D. and Geoffrey J. Golson, Ph.D.  2008. [CA][BC]

23. M.E. Pearce, A.K. Salem. Stem Cells and Iowa. Invited review for Encyclopedia of Stem Cell Research. Sage Publications. Edited by Clive Niels Svendsen, Ph.D., Allison D. Ebert, Ph.D. and Geoffrey J. Golson, Ph.D.  2008. [CA][BC]

22. A.K. Salem. Biopharmaceutical Drug Design and Development 2nd Ed. Journal of Medicinal Chemistry. 2008. [CA][R][IF = 5.447]

21. A.K. Salem. Frontiers in Drug Design and Discovery. Vol. 3 Journal of Medicinal Chemistry. 51(4):1073. 2008.  [CA][R][IF = 5.447 ]

 

2007

 

20. X.Q. Zhang, J. Intra, A.K. Salem. Conjugation of Polyamidoamine Dendrimers on Biodegradable Microparticles for Non-Viral Gene Delivery. Bioconjugate Chemistry. 2007 Nov-Dec;18(6):2068-76.  [CA][IF = 4.53]

19. M.E. Pearce, J.B. Melanko, A.K. Salem. Biomedical Applications of Multifunctional Nanorods. Pharmaceutical Research. 2007. Dec; 24(12):2335-52. [CA][R][IF = 3.42]

18. X.Q Zhang, C.E. Dahle, G.J. Weiner, A.K. Salem. A Comparative Study on the Immune Response Stimulated from Co-delivery of CpG ODN and Antigens using Fusion Molecules or Biodegradable Microparticles. Journal of Pharmaceutical Sciences. 2007 Dec;96(12):3283-92. [CA][IF = 2.59]

17. X.Q. Zhang, C.E. Dahle, N.K. Baman, N. Rich, G.J. Weiner, A.K. Salem. Potent Antigen-Specific Immune Responses Stimulated by Co-delivery of CpG ODN and Antigens in Degradable Microparticles.  Journal of Immunotherapy. 30 (5): 469-478 July/August 2007. [CA][IF = 3.354]

16. J.B. Melanko, M.E. Pearce, A.K. Salem. Nanotubes/Nanorods/Nanofibers/Fullerenes for Nanoscale Drug Delivery. Invited Chapter in the Book entitled "Nanotechnology in Drug Delivery". Springer Science/AAPS. Edited by Melgardt M. de Villiers, and Glen S. Kwon. 2007.  [CA][BC]

15. M. Popescu, A.K. Salem. Nanostructure Enabled Vaccines. Invited Chapter in the "Exploring Nano-Biotechnology Multimedia Encyclopedia. iMediasoft. 2007. [CA][BC]

14. A.K. Salem, M.K. Salem, H.K. Salem, S. Tapya. New Technologies and Therapies for Cancer. Invited review for Encyclopedia of Cancer and Society. Sage Publications. Edited by J. Geoffrey Golson and Graham A. Colditz. 2007. [CA LA][BC]

 

2006

 

13. N.K. Baman, G.B. Schneider, T.L. Terry, R. Zaharias, A.K. Salem. Spatial Control over Cell Attachment by Partial Solvent Entrapment of Poly Lysine in Microfluidic Channels. International Journal of Nanomedicine. 1 (2) APR 2006. [CA][IF = 4.32 ]

12. J. Sinclair, A.K. Salem. Rapid Localized Cell Trapping on Biodegradable Polymers Using Cell Surface Derivatization and Microfluidic Networking. Biomaterials 27 2090-2094 MAR 2006. [CA][IF = 8.387]

11. A.K. Salem, K.W. Leong. Polymer Scaffolds for Tissue Engineering and Gene Delivery. Invited Chapter in the Book entitled "Scaffolding in Tissue Engineering". Marcel Dekker. Edited by Jennifer Elisseeff and Peter X. Ma. 2006. [CA][BC]

10. A.K. Salem. Frontiers in Drug Design and Discovery. Vol. 2 Journal of Medicinal Chemistry. 2006. [CA][R][IF = 5.447]

 

2005


9. A.K. Salem, C.F. Hung, T.W. Kim, T.C. Wu, P.C. Searson, K.W. Leong. Multi-Component Nanorods for Vaccination Applications. Nanotechnology. 4 (16): 484-487 APR 2005. [LA CA][IF = 3.573]

8. A. Hultgren, M. Tanase, E.J. Felton, K. Bhadriraju, A.K. Salem, C.S. Chen, D.H. Reich. Optimization of Yield in Magnetic Cell Separations using Nickel Nanowires of Different Lengths. Biotechnology Progress. 21 (2): 509-515. MAR-APR 2005.  [IF = 2.167]

 

2004

 

7. A.K. Salem, M. Chen, J. Hayden, K.W. Leong, and P.C. Searson. Directed Assembly of Multi-Segment Au/Pt/Au Nanowires. Nanoletters. 4 (6): 1163-1165 JUN 2004. [LA][IF = 13.592 ]

6. A.K. Salem, J. Chao, K.W. Leong, and P.C. Searson. Receptor Mediated Self-Assembly of Multi-Component Magnetic Nanowires. Advanced Materials.  FEB 2004, 16, 3. [LA][IF = 17.49]

 

2003

 

5. A.K. Salem, P.C. Searson and K.W. Leong. Multifunctional Nanorods for Gene Delivery. Nature Materials.  OCT 2003, 2, 668-671. [LA][IF = 38.89]

4. H.S. Sakhalkar, M.K. Dalal, A.K. Salem, R. Ansari, J. Fu, M.F. Kiani, J. Hanes, K.M. Shakesheff and D.J. Goetz. Leukocyte Inspired Therapeutic Particles that Selectively and Avidly Adhere to Inflamed Endothelium in Vitro and in Vivo.  Proceedings of the National Academy of Sciences. DEC 2003, 100, 26:15895-15900 [IF = 9.423]

3. A.K. Salem, F.R.A.J. Rose, R. Oreffo, X. Yang, M.C. Davies, J.R. Mitchell, C.J. Roberts, S. Stolnik, S.J.B. Tendler, P.M. Williams and K.M. Shakesheff. Porous Polymer and Cell Composites that Self assemble In Situ. Advanced Materials. FEB 2003, 15, 3. [LA][IF = 17.49]

 

2002

 

2. A.K. Salem, R. Stevens, R.G. Pearson, M.C. Davies, S.J.B. Tendler and K.M. Shakesheff. Interactions of 3T3 Fibroblasts and Endothelial with Defined Pore Features.  Journal of Biomedical Materials Research. 61 (2) 212-217 AUG 2002. [LA][IF = 3.36]

 

2001

 

1. A.K. Salem, S.M. Cannizzaro, M.C. Davies, S.J.B. Tendler, C.J. Roberts, P.M. Williams and K.M. Shakesheff. Synthesis and Characterisation of a Degradable Biotinylated Polylactic acid-Polyethylene Glycol Copolymer. Biomacromolecules. SUM 2001, 2, 575-580. [LA][IF = 5.75]

 

 


Blog Postings

3. AAPS Blog: Nanoparticles in Vaccine Delivery. 2015

2. AAPS Blog: A Vaccine for Dust Mite Allergy-Induced Asthma Attacks. 2014

1. AAPS Blog: Biodegradable Particles: The Future of Vaccine Delivery. 2013

 

 


Patents and Technologies Available for Licensing

 

UIRF available technologies for licensing: https://research.uiowa.edu/uirf/pages/technologies/i/aliasger-salem/

 

15. BLEBBISTATIN LOADED PLGA NANOPARTICLES FOR THE PREVENTION OF SCAR FORMATION
Blebbistatin is a cell-permeable inhibitor of class-II myosins which are known to play a key role in the development of scars during the wound healing process.
UIRF Case #:16018HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Edward Sander, Aliasger Salem, James Martin


14. MIRNA-200 FAMILY MEMBERS TREAT BONE & CARTILAGE LOSS BY PREVENTING PRO-INFLAMMATORY SIGNALING
Long-term inflammatory signaling has been shown to promote the loss of bone and related tissues and prevent their regeneration.
UIRF Case #:15081HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Liu Hong, Brad Amendt, Aliasger Salem, Kim Brogden, Christopher Barwacz, Gustavo Oritz, Satheesh Elangovan, Thad Sharp


13. A VACCINE AGAINST DUST MITE ALLERGY
Poly (lactic-co-glycolic acid) microparticles filled with CpG adjuvant and coated with dust mite antigen produce a favored TH1 immune response.
UIRF Case #:15078HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Peter Thorne, Aliasger Salem, Xuefang Jing, Vijaya Joshi, Amaraporn Wongrakpanich


12. A HYDROGEL-BASED COMPOSITION FOR THE REGENERATION OF ARTICULAR CARTILAGE IN VIVO
A chondrocyte chemoattractant in combination with a chondrogenic factor induce existing chondrocytes to repair traumatized cartilage tissue.
UIRF Case #:15065HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): James Martin, Yin Yu, Dong Seol, Aliasger Salem, Behnoush Sourkohi, Anh-Vu Do


11. RNA BASED BIOMATERIAL FOR TISSUE ENGINEERING APPLICATIONS
The local delivery of chemically modified RNA (cmRNA) encoding tissue-specific growth factors can stimulate desired tissue regeneration from residual living cells.
UIRF Case #:15001HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Satheesh Elangovan, Sheetal D'mello, Anh-Vu Do, Liu Hong, Behnoush Khorsand-Sourkohi, Aliasger Salem


10. A FABRICATION METHOD FOR PERFUSABLE HYBRID TISSUE PRODUCTION
This process requires only cells and extracellular matrix components, producing a more natural tissue than achieved through scaffolding approaches.
UIRF Case #:14035HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Ibrahim Ozbolat, Howard Chen, Yin Yu, Yahui Zhang, Nicholas Zavazava, Liu Hong, Aliasger Salem, Adil Akkouch, Kazim Moncal


9. MITOCHONDRIAL TARGETED NANOPARTICLES THAT KNOCKDOWN CAMKII ACTIVITY
This delivery system targets CaMKII inhibition to cellular mitochondria, where it is believed to be most effective.
UIRF Case #:14001HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Mei-ling Joiner, Mark Anderson, Aliasger Salem, Amaraporn, Wongrakpanich, Frederick Domann, Duane Hall, Olha Koval, Douglas Spitz


8. A MULTI-ARM BIOPRINTER FOR 3D HYBRID TISSUE PRINTING
The utilization of two independent arms for printing cells allows for the introduction of a vascular network for the tissue structure, which enhances long term cell viability.
UIRF Case #:13097HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Ibrahim Ozbolat, Howard Chen, Yin Yu, Yahui Zhang, Nicholas Zavazava, Liu Hong, Aliasger Salem, Adil Akkouch, Kazim Moncal


7. A NOVEL POLYMER STRUCTURE FORMED BY POLY(SULFENAMIDE)S OR POLY(DIAMINOSULFIDE)S
These polymers demonstrate biodegradability and biocompatibility features that are desirable for potential drug delivery vehicles.
UIRF Case #:11022 & 12036HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Ned Bowden, Aliasger Salem, Jun Yoo, Denison Kuruvilla, Tyler Graf, Sheetal D'Mello


6. MICROPARTICLE-BASED VACCINE DELIVERY SYSTEM
Encapsulation of antigen and adjuvant in PLGA microparticles improves durability and efficacy.
UIRF Case #:10052HTML (OVERVIEW)PDF (TECHNOLOGY DETAIL)

Inventor(s): Aliasger Salem, George Weiner, Sean Geary, Caitlin Lemke, Yogita Krishnamachari

 

 

Patents

1.    J. Yoo, D. Kuruvilla, A.K. Salem, N. Bowden. New Biodegradable Polymers With Sulfenamide Bonds for Drug Delivery Applications WO 2, 012,115,806 (2016)

2.    A.K. Salem, S. Geary, G. Weiner, C. Lemke, Y. Krishnamachari. Biodegradable Particulate Formulations. US 9.572,894 B2 (2017).

3.    A. Sandler, G. Weiner, A.K. Salem. Bioactive Sutures for the Treatment of Cancer. WO 2,009, 097, 545 (2009)

4.    A.K. Salem, K.W. Leong and P.C Searson. Methods and Products for Delivering Biological Molecules to Cells using Multicomponent Nanostructures. 7,344,887 (2008)

5.    K.M. Shakesheff and A.K. Salem. Porous Matrix Composed of Crosslinked Particles (Tissue Scaffold). US7785617 B2 (2010) 

6.    M.E. Anderson, M.A. Joiner, A.K. Salem, A. Wongrakpanich, F.E. Domann, D.D. Hall, O.M. Koval, D.R. Spitz. Mitochondrial-targeted cationic nanoparticles comprising CaMKII inhibitors and uses thereof for treating and preventing diseases and disorders associated with CaMKII activity. US 9168307 B2 (2015)

7.    J.A. Martin, Y. Yu, D.R. Seol, A.K. Salem, B. Khorsand Sourkohi, A. Do, M. Brouillette. Methods for the regeneration of articular cartilage in vivo. WO2016112176 A1 (2016).